ArticleBiomedicines2023
Insights from a Case of Good's Syndrome (Immunodeficiency with Thymoma).
Article in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 13 citations in OpenAlex.
- Clinical characteristics and risk factors of cytomegalovirus infection in patients with good syndrome.BMC immunology · 2026Article
- Recurrent invasive fungal infection with locally advanced thymoma: diagnostic challenges in complex mediastinal disease.Breathe (Sheffield, England) · 2026Article
- Good's syndrome and infections in a large retrospective cohort of thymoma.Frontiers in immunology · 2026Article
- Good syndrome combined with multiple microbial pulmonary infections: case report and review of the literature.Immunologic research · 2024Review
- Thymoma with recurrent opportunistic infections-a case report.Oxford medical case reports · 2024Article
- COVID-19 in patients with thymic epithelial tumors with or without Good's syndrome: a single-center retrospective study.BMC cancer · 2024Article
- Article
- A Tribute to Two Master Teachers of Immunology.Biomedicines · 2023Article
- In-depth blood immune profiling of Good syndrome patients.Frontiers in immunology · 2023Article
- Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections.Case reports in oncologyArticle
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Immunodeficiency with thymoma was described by R.A. Good in 1954 and is also named after him. The syndrome is characterized by hypogammaglobulinemia associated with thymoma and recurrent infections, bacterial but also viral, fungal and parasitic. Autoimmune diseases, mainly pure red cell aplasia, other hematological disorders and erosive lichen planus are a common finding. We describe here a typical case exhibiting all these clinical features and report a detailed immunophenotypic assessment, as well as the positivity for autoantibodies against three cytokines (IFN-alpha, IL-6 and GM-CSF), which may add to known immune abnormalities. A review of the published literature, based on case series and immunological studies, offers some hints on the still unsolved issues of this rare condition.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.