ReviewBiomedicines2023
Noninvasive Electrical Stimulation Neuromodulation and Digital Brain Technology: A Review.
Review in Biomedicines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- [Progresses on temporal interference electromagnetic stimulation for non-invasive deep brain function modulation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2025Pooled it
- Emerging technologies and neuroscience-based approaches in dyslexia: a narrative review toward integrative and personalized solutions.Frontiers in human neuroscience · 2025Pooled it
- Bladder Digital Twins for Neuromodulation: Current Platforms and a Roadmap to Closed-Loop Therapy.International neurourology journal · 2026Article
- Polydopamine Nanotubes: Multifunctional Smart Nanotransducers for Cellular Activity Modulation.ACS nano · 2026Article
- MXene Nanomaterial Interfaces: Pioneering Neural Signal Recording for Brain-Computer Interfaces and Cognitive Therapy.Topics in current chemistry (Cham) · 2026Review
- Demonstration of Alpha-Band Entrainment via Low-Field Magnetic Stimulation: A Simulation-Driven Proof of Concept.Bioengineering (Basel, Switzerland) · 2026Article
- [A review of noninvasive brain-computer interfaces combined with transcranial electrical stimulation for neural rehabilitation].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026Review
- Optoelectronic Interfaces for Nongenetic Modulation of Excitable Tissues.Small methods · 2026Review
- Cognition, Diagnosis, and Treatment of Alzheimer's Disease: A Review.Recent patents on biotechnology · 2026Review
- Article
- Editorial forBrain sciences · 2025Article
- From innovation to clinic: Emerging strategies harnessing electrically conductive polymers to enhance electrically stimulated peripheral nerve repair.Materials today. Bio · 2025Article
- The intrinsic spatiotemporal structure of cognitive functions inspires the intervention of brain functions.Frontiers in neurology · 2025Article
- Pain and the autonomic nervous system. The role of non-invasive neuromodulation with NESA microcurrents.Frontiers in pain research (Lausanne, Switzerland) · 2025Article
- Computational analysis of electrode structure and configuration for efficient and localized neural stimulation.Biomedical engineering letters · 2024Article
- General Treatments Promoting Independent Living in Parkinson's Patients and Physical Therapy Approaches for Improving Gait-A Comprehensive Review.Medicina (Kaunas, Lithuania) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
We review the research progress on noninvasive neural regulatory systems through system design and theoretical guidance. We provide an overview of the development history of noninvasive neuromodulation technology, focusing on system design. We also discuss typical cases of neuromodulation that use modern noninvasive electrical stimulation and the main limitations associated with this technology. In addition, we propose a closed-loop system design solution of the "time domain", "space domain", and "multi-electrode combination". For theoretical guidance, this paper provides an overview of the "digital brain" development process used for noninvasive electrical-stimulation-targeted modeling and the development of "digital human" programs in various countries. We also summarize the core problems of the existing "digital brain" used for noninvasive electrical-stimulation-targeted modeling according to the existing achievements and propose segmenting the tissue. For this, the tissue parameters of a multimodal image obtained from a fresh cadaver were considered as an index. The digital projection of the multimodal image of the brain of a living individual was implemented, following which the segmented tissues could be reconstructed to obtain a "digital twin brain" model with personalized tissue structure differences. The "closed-loop system" and "personalized digital twin brain" not only enable the noninvasive electrical stimulation of neuromodulation to achieve the visualization of the results and adaptive regulation of the stimulation parameters but also enable the system to have individual differences and more accurate stimulation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.