Evidence map›Paper›PMID 37371423›Full record

ArticleBrain sciences2023

Do Individuals with Spinal Cord Injury Benefit from Semi-Immersive Virtual Reality Cognitive Training? Preliminary Results from an Exploratory Study on an Underestimated Problem.

Maria Grazia Maggio, Mirjam Bonanno, Alfredo Manuli, Maria Pia Onesta, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò

Registry-linked trialAbstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06838975 (Effectiveness of Virtual Reality Rehabilitation to Improve Cognitive, Emotional, Relational, and Motor Domains in Patients With Neurological and Neurodegenerative Disorders), which is not on this map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06838975 naactive not recruitingnot on this mapstarted 2025, after this paper: background citation

Effectiveness of Virtual Reality Rehabilitation to Improve Cognitive, Emotional, Relational, and Motor Domains in Patients With Neurological and Neurodegenerative Disorders

TypeinterventionalSponsorIRCCS Centro Neurolesi Bonino PulejoRan2025 to 2028Enrolled328ConditionsAcquired Brain Injuries, Spinal Cord Injury, Multiple Sclerosis, Parkinson DiseaseArmsVR Training, traditional cognitive and motor rehabilitation following standard clinical practices
3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maria Grazia MaggioDepartment of Biomedical and Biotechnological Science, University of Catania, Via S. Sofia 64, 95125 Catania, Italy.ORCID 0000-0003-0757-2389
Mirjam BonannoIRCCS Centro Neurolesi "Bonino Pulejo", S. S. 113, Contrada Casazza, 98124 Messina, Italy.ORCID 0000-0002-3284-9741
Alfredo ManuliRehabilitation Unit, AOU Policlinico "G. Martino", 98124 Messina, Italy.
Maria Pia OnestaSpinal Cord Unit, Cannizzaro Hospital, 95126 Catania, Italy.
Rosaria De LucaIRCCS Centro Neurolesi "Bonino Pulejo", S. S. 113, Contrada Casazza, 98124 Messina, Italy.
Angelo QuartaroneIRCCS Centro Neurolesi "Bonino Pulejo", S. S. 113, Contrada Casazza, 98124 Messina, Italy.
Rocco Salvatore CalabròIRCCS Centro Neurolesi "Bonino Pulejo", S. S. 113, Contrada Casazza, 98124 Messina, Italy.ORCID 0000-0002-8566-3166

Funding

Current Research Funds 2023, Ministry of Health, Italy This research does not have a grant number
6 · The paper itself

Abstract

A spinal cord injury (SCI) is damage to any part of the spinal cord, caused by traumatic or non-traumatic events. Clinically, SCI is associated with partial or complete loss of motor, sensory, and autonomic functions below the site of injury. However, cognitive alterations in specific domains can also occur. The aim of this study was to evaluate the effects of semi-immersive virtual reality (VR) cognitive training (using the BTS Nirvana, Italy) in promoting global functional recovery in patients with SCI. Forty-two SCI patients were included in this retrospective case-control study, and the analysis was carried out using an electronic data retrieval system. The enrolled patients were divided into two groups with the same demographic and medical characteristics: the control group (CG: 21 patients) participated in traditional therapy, whereas the experimental group (EG: 21 patients) received training using semi-immersive VR. In both groups, there were patients with A- or B-grade impairments according to the American Spinal Injury Association (ASIA) scale. Both study groups underwent the same amount of cognitive training (but using a different type of training: conventional vs. innovative), consisting of three weekly sessions for eight weeks (24 sessions in total), each session lasting approximately sixty minutes, as well as the same amount of physiotherapy. The effect of the two treatments (EG/CG) was significantly different in global cognitive functioning (MOCA:

Indexed as

cognitive trainingneurorehabilitationsemi-immersive virtual realityspinal cord injury

Identifiers

PMID37371423
PMCPMC10296140

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.