Evidence map›Paper›PMID 37371350›Full record

ArticleBrain sciences2023

Machine Learning Prediction of Estimated Risk for Bipolar Disorders Using Hippocampal Subfield and Amygdala Nuclei Volumes.

Fabian Huth, Leonardo Tozzi, Michael Marxen, Philipp Riedel, Kyra Bröckel, Julia Martini, Christina Berndt, Cathrin Sauer, Christoph Vogelbacher, Andreas Jansen and 25 more

Abstract read
In one paragraph

Article in Brain sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Observational
  2. Review
  3. Article
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  5. Article
  6. Review
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  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors.

Fabian HuthDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.
Leonardo TozziDepartment of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA.ORCID 0000-0002-9429-6476
Michael MarxenDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.ORCID 0000-0001-8870-0041
Philipp RiedelDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.
Kyra BröckelDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.
Julia MartiniDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.
Christina BerndtDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.
Cathrin SauerDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.
Christoph VogelbacherCore-Facility Brainimaging, Faculty of Medicine, University of Marburg, 35037 Marburg, Germany.ORCID 0000-0002-3191-1400
Andreas JansenCore-Facility Brainimaging, Faculty of Medicine, University of Marburg, 35037 Marburg, Germany.
Tilo KircherCenter for Mind, Brain and Behavior (CMBB), University of Marburg and University Giessen, 35039 Marburg, Germany.ORCID 0000-0002-2514-2625
Irina FalkenbergCenter for Mind, Brain and Behavior (CMBB), University of Marburg and University Giessen, 35039 Marburg, Germany.ORCID 0000-0003-3699-0803
Florian Thomas-OdenthalCenter for Mind, Brain and Behavior (CMBB), University of Marburg and University Giessen, 35039 Marburg, Germany.
Martin LambertDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.
Vivien KraftDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.ORCID 0000-0002-5815-1026
Gregor LeichtDepartment of Psychiatry and Psychotherapy, University Medical Center Hamburg-Eppendorf, 20251 Hamburg, Germany.ORCID 0000-0002-5104-9336
Christoph MulertCenter for Mind, Brain and Behavior (CMBB), University of Marburg and University Giessen, 35039 Marburg, Germany.
Andreas J FallgatterDepartment of Psychiatry, Tuebingen Center for Mental Health, University of Tuebingen, 72074 Tuebingen, Germany.
Thomas EthoferDepartment of Psychiatry, Tuebingen Center for Mental Health, University of Tuebingen, 72074 Tuebingen, Germany.
Anne RauDepartment of Psychiatry, Tuebingen Center for Mental Health, University of Tuebingen, 72074 Tuebingen, Germany.
Karolina LeopoldDepartment of Psychiatry, Psychotherapy and Psychosomatic Medicine, Vivantes Hospital Am Urban and Vivantes Hospital Im Friedrichshain, Charité-Universitätsmedizin, 10117 Berlin, Germany.
Andreas BechdolfDepartment of Psychiatry, Psychotherapy and Psychosomatic Medicine, Vivantes Hospital Am Urban and Vivantes Hospital Im Friedrichshain, Charité-Universitätsmedizin, 10117 Berlin, Germany.
Andreas ReifDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University Frankfurt, University Hospital, 60323 Frankfurt, Germany.
Silke MaturaDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University Frankfurt, University Hospital, 60323 Frankfurt, Germany.
Silvia BiereDepartment of Psychiatry, Psychosomatic Medicine and Psychotherapy, Goethe University Frankfurt, University Hospital, 60323 Frankfurt, Germany.
Felix BermpohlDepartment of Psychiatry and Psychotherapy, Charité Campus Mitte, Charité University Medicine, 10117 Berlin, Germany.
Jana FiebigDepartment of Psychiatry and Psychotherapy, Charité Campus Mitte, Charité University Medicine, 10117 Berlin, Germany.
Thomas StammDepartment of Psychiatry and Psychotherapy, Charité Campus Mitte, Charité University Medicine, 10117 Berlin, Germany.
Christoph U CorrellDepartment of Child and Adolescent Psychiatry, Charité Universitätsmedizin Berlin, 10117 Berlin, Germany.ORCID 0000-0002-7254-5646
Georg JuckelDepartment of Psychiatry, Psychotherapy and Preventive Medicine, LWL University Hospital, Ruhr-University, 44791 Bochum, Germany.
Vera FlasbeckDepartment of Psychiatry, Psychotherapy and Preventive Medicine, LWL University Hospital, Ruhr-University, 44791 Bochum, Germany.ORCID 0000-0001-6405-4567
Philipp RitterDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.ORCID 0000-0003-4286-5830
Michael BauerDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.
Andrea PfennigDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.
Pavol MikolasDepartment of Psychiatry and Psychotherapy, Carl Gustav Carus University Hospital, Technische Universität Dresden, 01062 Dresden, Germany.ORCID 0000-0002-3974-7115

Funding

Deutsche Forschungsgemeinschaft 178833530Deutsche Forschungsgemeinschaft 402170461Federal Ministry of Education and Research 01EE1404AFederal Ministry of Education and Research 01EE1404EFederal Ministry of Education and Research 01EE1404F
6 · The paper itself

Abstract

The pathophysiology of bipolar disorder (BD) remains mostly unclear. Yet, a valid biomarker is necessary to improve upon the early detection of this serious disorder. Patients with manifest BD display reduced volumes of the hippocampal subfields and amygdala nuclei. In this pre-registered analysis, we used structural MRI (

Indexed as

amygdala nucleibipolar riskhippocampal subfieldsmachine learningMRI

Identifiers

PMID37371350
PMCPMC10296102

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.