Evidence map›Paper›PMID 37371109›Full record

ArticleCells2023

Association between

Katja Zappe, Katharina Pühringer, Simon Pflug, Daniel Berger, Andreas Böhm, Sabine Spiegl-Kreinecker, Margit Cichna-Markl

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
5.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Cells · 2026
    Article
  4. Promoter Methylation-Expression Coupling of Gliogenesis Genes inInternational journal of molecular sciences · 2026
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. DNA Methylation and Transcript Variant Analysis ofInternational journal of molecular sciences · 2025
    Article
  11. Association of Intergenic and IntragenicInternational journal of molecular sciences · 2025
    Article
  12. Article
  13. OMethods in molecular biology (Clifton, N.J.) · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Association ofCancers · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Katja ZappeDepartment of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-2002-9727
Katharina PühringerDepartment of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria.
Simon PflugDepartment of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0003-3421-2346
Daniel BergerDepartment of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria.
Andreas BöhmDepartment of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria.
Sabine Spiegl-KreineckerDepartment of Neurosurgery, Kepler University Hospital GmbH, Johannes Kepler University, 4040 Linz, Austria.
Margit Cichna-MarklDepartment of Analytical Chemistry, Faculty of Chemistry, University of Vienna, 1090 Vienna, Austria.ORCID 0000-0001-8699-674X
University of Vienna · ATKepler Universitätsklinikum · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The repair protein O6-methylguanine-DNA methyltransferase (MGMT) is regulated epigenetically, mainly by the methylation of the

Indexed as

Brain NeoplasmsGlioblastomaDNA MethylationDNA Modification MethylasesDNA Repair EnzymesHumansPromoter Regions, GeneticTumor Suppressor ProteinsDNA Modification MethylasesDNA Repair EnzymesMGMT protein, humanTumor Suppressor ProteinsbiomarkerDNA methylationenhancerenhancer methylationglioblastomahigh resolution meltingMGMToverall survivalprognostic biomarkerpyrosequencing

Identifiers

PMID37371109
PMCPMC10297309
OpenAlexW4380877929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.