Evidence map›Paper›PMID 37371071›Full record

ArticleCells2023

Analysis of Plasma Proteins Involved in Inflammation, Immune Response/Complement System, and Blood Coagulation upon Admission of COVID-19 Patients to Hospital May Help to Predict the Prognosis of the Disease.

Daniele Castro di Flora, Aline Dionizio, Heloisa Aparecida Barbosa Silva Pereira, Thais Francini Garbieri, Larissa Tercilia Grizzo, Thiago José Dionisio, Aline de Lima Leite, Licia C Silva-Costa, Nathalia Rabelo Buzalaf, Fernanda Navas Reis and 4 more

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. The Impact of Serum/Plasma Proteomics on SARS-CoV-2 Diagnosis and Prognosis.International journal of molecular sciences · 2024
    Review
  7. Article
  8. Plasma Proteins Associated with COVID-19 Severity in Puerto Rico.International journal of molecular sciences · 2024
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Daniele Castro di FloraDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.
Aline DionizioDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.ORCID 0000-0002-8687-0124
Heloisa Aparecida Barbosa Silva PereiraDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.ORCID 0000-0002-1839-2546
Thais Francini GarbieriDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.ORCID 0000-0003-4507-5148
Larissa Tercilia GrizzoDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.ORCID 0000-0002-1469-5224
Thiago José DionisioDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.
Aline de Lima LeiteNebraska Center for Integrated Biomolecular Communication, University of Nebraska-Lincoln, Lincoln, NE 68503, USA.ORCID 0000-0002-2112-1309
Licia C Silva-CostaLaboratory of Neuroproteomics, Institute of Biology, Department of Biochemistry and Tissue Biology, University of Campinas, Campinas 13083-862, Brazil.
Nathalia Rabelo BuzalafDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.
Fernanda Navas ReisDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.
Virginia Bodelão Richini PereiraCenter of Regional Laboratories II, Adolfo Lutz Institute, Bauru 17015-110, Brazil.ORCID 0000-0001-8312-7397
Deborah Maciel Cavalcanti RosaTherapy and Diagnosis Unit, Bauru State Hospital, Bauru 17033-360, Brazil.
Carlos Ferreira Dos SantosDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.ORCID 0000-0002-0405-3500
Marília Afonso Rabelo BuzalafDepartment of Biological Sciences, Bauru School of Dentistry, University of São Paulo, Bauru 17012-901, Brazil.ORCID 0000-0002-5985-3951
Universidade de São Paulo · BRInstituto Adolfo Lutz · BRUniversidade Estadual de Campinas (UNICAMP) · BRUniversity of Nebraska–Lincoln · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of new approaches allowing for the early assessment of COVID-19 cases that are likely to become critical and the discovery of new therapeutic targets are urgently required. In this prospective cohort study, we performed proteomic and laboratory profiling of plasma from 163 COVID-19 patients admitted to Bauru State Hospital (Brazil) between 4 May 2020 and 4 July 2020. Plasma samples were collected upon admission for routine laboratory analyses and shotgun quantitative label-free proteomics. Based on the course of the disease, the patients were divided into three groups: (a) mild (

Indexed as

COVID-19Blood CoagulationBlood ProteinsComplement System ProteinsHospitalsHumansImmunityInflammationProspective StudiesProteomicsSARS-CoV-2Blood ProteinsComplement System ProteinsbiomarkerCOVID-19plasmaprognosisproteomics

Identifiers

PMID37371071
PMCPMC10297236
OpenAlexW4380372763

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.