Evidence map›Paper›PMID 37371057›Full record

ArticleCells2023

Interleukin-36 Receptor Signaling Attenuates Epithelial Wound Healing in C57BL/6 Mouse Corneas.

Qi Chen, Nan Gao, Fu-Shin Yu

Open access · goldAbstract read
In one paragraph

Article in Cells, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Qi ChenDepartments of Ophthalmology, Visual and Anatomical Sciences, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Nan GaoDepartments of Ophthalmology, Visual and Anatomical Sciences, School of Medicine, Wayne State University, Detroit, MI 48201, USA.ORCID 0000-0003-0259-3316
Fu-Shin YuDepartments of Ophthalmology, Visual and Anatomical Sciences, School of Medicine, Wayne State University, Detroit, MI 48201, USA.
Wayne State University · US

Funding

VISION RESEARCH--COREP30EY004068 · NEI · WAYNE STATE UNIVERSITY · PI LINDA D HAZLETT · 1985 to 2026
$13.2M
MOLECULAR REGULATION OF CORNEAL WOUND HEALINGR01EY010869 · NEI · WAYNE STATE UNIVERSITY · PI YU, FU-SHIN X · 1995 to 2023
$7.7M
Mechanisms of flagellin-induced protection against microbial keratitisR01EY017960 · NEI · WAYNE STATE UNIVERSITY · PI YU, FU-SHIN X · 2008 to 2020
$4.8M
NEI NIH HHS P30 EY004068NEI NIH HHS R01 EY010869NEI NIH HHS R01 EY017960
6 · The paper itself

Abstract

The IL-36 cytokines are known to play various roles in mediating the immune and inflammatory response to tissue injury in a context-dependent manner. This study investigated the role of IL-36R signaling in mediating epithelial wound healing in normal (NL) and diabetic (DM) C57BL/6 mouse corneas. The rate of epithelial wound closure was significantly accelerated in IL-36 receptor-deficient (IL-36R

Indexed as

CorneaInterleukin 1 Receptor Antagonist ProteinAnimalsCytokinesMiceMice, Inbred C57BLWound HealingCytokinesInterleukin 1 Receptor Antagonist Proteindiabetic keratopathyinterleukin-36wound healing

Identifiers

PMID37371057
PMCPMC10297323
OpenAlexW4380048091

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.