Evidence map›Paper›PMID 37371023›Full record

ArticleDiagnostics (Basel, Switzerland)2023

Determination of Anti-Xa Inhibitor Plasma Concentrations Using a Universal Edoxaban Calibrator.

Annika Burger, Jan-Dirk Studt, Adriana Mendez, Lorenzo Alberio, Pierre Fontana, Walter A Wuillemin, Adrian Schmidt, Lukas Graf, Bernhard Gerber, Cédric Bovet and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Annika BurgerDepartment of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Jan-Dirk StudtDivision of Medical Oncology and Hematology, University Hospital Zurich, University of Zurich, 8006 Zurich, Switzerland.
Adriana MendezInstitute for Laboratory Medicine, Kantonsspital Aarau, 5001 Aarau, Switzerland.
Lorenzo AlberioService and Central Laboratory of Hematology, Centre Hospitalier Universitaire Vaudois (CHUV), 1011 Lausanne, Switzerland.ORCID 0000-0001-9686-9920
Pierre FontanaDivision of Angiology and Hemostasis, Geneva University Hospital, 1205 Geneva, Switzerland.ORCID 0000-0003-1546-0774
Walter A WuilleminDivision of Hematology, Hematology Laboratory, Cantonal Hospital of Lucerne, University of Bern, 3012 Bern, Switzerland.
Adrian SchmidtInstitute of Laboratory Medicine, Clinic of Medical Oncology and Hematology, Municipal City Hospital Zurich Triemli, 8063 Zurich, Switzerland.ORCID 0000-0002-6315-2592
Lukas GrafCentre for Laboratory Medicine, 9001 St. Gallen, Switzerland.
Bernhard GerberClinic of Hematology, Oncology Institute of Southern Switzerland, 6500 Bellinzona, Switzerland.ORCID 0000-0001-5418-0949
Cédric BovetDepartment of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.
Thomas C SauterDepartment of Emergency Medicine, Inselspital, Bern University Hospital, 3010 Bern, Switzerland.
Nikolaus B BinderTechnoclone Herstellung von Diagnostika und Arzneimitteln GmbH, 1230 Vienna, Austria.
Michael NaglerDepartment of Clinical Chemistry, Inselspital, Bern University Hospital, University of Bern, 3010 Bern, Switzerland.ORCID 0000-0003-4319-2367

Funding

Research Fund Haematology Cantonal Hospital Lucerne N/A
6 · The paper itself

Abstract

A universal calibrator for the determination of all anti-Xa inhibitors would support laboratory processes. We aimed to test the clinical performance of an anti-Xa assay utilizing a universal edoxaban calibrator to determine clinically relevant concentrations of all anti-Xa inhibitors. Following a pilot study, we enrolled 553 consecutive patients taking rivaroxaban, edoxaban, or apixaban from nine study centers in a prospective cross-sectional study. The Technochrom

Indexed as

anticoagulants introductionanti-Xa assayapixabandiagnostic accuracyedoxabanlaboratory monitoringrivaroxaban

Identifiers

PMID37371023
PMCPMC10297422

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.