ReviewDiagnostics (Basel, Switzerland)2023
Ultrasound Elastography to Assess Age of Deep Vein Thrombosis: A Systematic Review.
Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 19 citations in OpenAlex.
- Ultrafast shear-wave elastography for pediatric deep vein thrombosis: a prospective feasibility study.Pediatric radiology · 2026Article
- Diagnostic Efficacy of Acoustic Radiation Force Impulse in Staging of Lower Limb Intramuscular Venous Thrombosis: A Single-Center Prospective Cohort Study.Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine · 2026Article
- Resolution of a femoral arteriovenous fistula secondary to chronic Iliac vein occlusion after stenting: a case report.BMC surgery · 2026Article
- ThrombUS+ Project: Toward Wearable Continuous Point-of-Care Monitoring for Deep Vein Thrombosis of the Lower Limb.Computational and structural biotechnology journal · 2026Article
- Evaluation of the stability of deep vein thrombosis based on computed tomography energy spectrum.Quantitative imaging in medicine and surgery · 2025Article
- Multiparametric Contrast-Free MRI Successfully Identifies Venous Thrombus Responsive to Lytic Therapy: From Mice to Humans.Circulation. Cardiovascular imaging · 2025Article
- Seeing the Unseen: Contrast-Free MRI for Predicting Thrombolytic Susceptibility.Circulation. Cardiovascular imaging · 2025Article
- Non-Invasive Characterization of Lower Extremity Deep Vein Thrombosis via Advanced Ultrasound Elastography: A Prospective Pilot Study.Internal and emergency medicine · 2025Article
- Nomogram-based prediction of the prognosis in patients with free floating venous thrombus after closed traumatic fracture.BMC medical imaging · 2025Article
- A finite element analysis model for magnetomotive ultrasound elastometry magnet design with experimental validation.Biomedical physics & engineering express · 2025Article
- Thrombus stiffness as an independent predictor of endovascular treatment success in hemodialysis fistulas: a study using ultrasound elastography.Ultrasonography (Seoul, Korea) · 2025Article
- Article
- Evaluating the stage of deep vein thrombosis: the diagnostic accuracy of shear wave elastography and super-microvascular imaging.Quantitative imaging in medicine and surgery · 2024Article
- The History of Diagnosing Venous Thromboembolism.Seminars in thrombosis and hemostasis · 2024Review
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimsDeep-vein thrombosis (DVT) is a widely diffused condition, and its accurate staging has major clinical and therapeutic implications. Ultrasound elastography (UE) is a rapidly evolving imaging technique that allows quantification of elastic tissue properties and could play a crucial role in determining thrombus age. The aim of this review is to find clinical evidence regarding the application of UE in the evaluation of DVT and its usefulness in differentiating thrombosis age.
methodsA literature search of clinical studies was performed to identify the ability of UE of discriminate acute, subacute, and chronic DVT. Heterogeneity and publication bias were calculated. In accordance with the study protocol, a qualitative analysis of the evidence was planned. The results were summarized with a comprehensive summary table of study characteristics and baseline characteristics of participant patients.
resultsNine studies matched the predetermined eligibility requirements for this systematic review regarding the risk of bias; the greatest criticalities were found within the domains of patient selection and index test. Based on the quality assessment, two publications were excluded from the qualitative synthesis because of the presence of significant applicability concerns. Among the seven studies that were considered eligible for qualitative synthesis, four evaluated strain elastography and three evaluated shear-wave elastography. Despite significant differences concerning study design, thrombus age definitions, and patient characteristics, nearly all studies demonstrated an increase in thrombus stiffness according to DVT age.
conclusionsUE could play a key role in routine ultrasound examination of DVT. The measurement of thrombus stiffness has a high biological plausibility and its use is supported by the finding of a correlation between the stiffness and the progression of the DVT age.
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