Evidence map›Paper›PMID 37370952›Full record

ReviewDiagnostics (Basel, Switzerland)2023

New Perspectives in Endoscopic Treatment of Gastroesophageal Reflux Disease.

Federica Calabrese, Valeria Poletti, Francesco Auriemma, Danilo Paduano, Carmine Gentile, Antonio Facciorusso, Gianluca Franchellucci, Alessandro De Marco, Luca Brandaleone, Andrew Ofosu and 8 more

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 7 institutions in 3 countries.

Federica CalabreseGastrointestinal Endoscopy Unit, Humanitas Mater Domini, 21053 Castellanza, Italy.
Valeria PolettiEndoscopy Unit, Humanitas Clinical and Research Center-IRCCS, 20089 Rozzano, Italy.
Francesco AuriemmaGastrointestinal Endoscopy Unit, Humanitas Mater Domini, 21053 Castellanza, Italy.
Danilo PaduanoGastrointestinal Endoscopy Unit, Humanitas Mater Domini, 21053 Castellanza, Italy.ORCID 0000-0003-2732-0840
Carmine GentileGastrointestinal Endoscopy Unit, Humanitas Mater Domini, 21053 Castellanza, Italy.
Antonio FacciorussoSection of Gastroenterology, Department of Medical Sciences, University of Foggia, 71100 Foggia, Italy.ORCID 0000-0002-2107-2156
Gianluca FranchellucciEndoscopy Unit, Humanitas Clinical and Research Center-IRCCS, 20089 Rozzano, Italy.
Alessandro De MarcoEndoscopy Unit, Humanitas Clinical and Research Center-IRCCS, 20089 Rozzano, Italy.
Luca BrandaleoneEndoscopy Unit, Humanitas Clinical and Research Center-IRCCS, 20089 Rozzano, Italy.ORCID 0009-0002-4432-3015
Andrew OfosuDivision of Digestive Diseases, University of Cincinnati, Cincinnati, OH 45219, USA.
Jayanta SamantaDepartment of Gastroenterology, Post Graduate Institute of Medical Education and Research, Chandigarh 160012, India.ORCID 0000-0002-9277-5086
Daryl RamaiDivision of Gastroenterology and Hepatology, University of Utah Health, Salt Lake City, UT 84132, USA.
Luca De LucaEndoscopic Unit, ASST Santi Paolo e Carlo, 20142 Milan, Italy.ORCID 0000-0002-3290-3103
Abed Al-LehibiKing Fahad Medical City, Faculty of Medicine, King Saud Bin Abduaziz University-Health Science, Riyadh 11525, Saudi Arabia.ORCID 0000-0002-4375-0384
Walter ZulianiGastrointestinal Endoscopy Unit, Humanitas Mater Domini, 21053 Castellanza, Italy.
Cesare HassanEndoscopy Unit, Humanitas Clinical and Research Center-IRCCS, 20089 Rozzano, Italy.
Alessandro RepiciEndoscopy Unit, Humanitas Clinical and Research Center-IRCCS, 20089 Rozzano, Italy.
Benedetto MangiavillanoGastrointestinal Endoscopy Unit, Humanitas Mater Domini, 21053 Castellanza, Italy.ORCID 0000-0003-0611-7448
Humanitas Mater Domini · ITHumanitas University · ITOspedale San Paolo · ITPost Graduate Institute of Medical Education and Research · INUniversity of Cincinnati · USUniversity of Foggia · ITUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastroesophageal reflux disease has a high incidence and prevalence in the general population. Clinical manifestations are heterogenous, and so is the response to medical treatment. Proton pump inhibitors are still the most common agents used to control reflux symptoms and for healing esophagitis, but they are not a one-size-fits-all solution for the disease. Patients with persistent troublesome symptoms despite medical therapy, those experiencing some adverse drug reaction, or those unwilling to take lifelong medications deserve valid alternatives. Anti-reflux Nissen fundoplication is an effective option, but the risk of adverse events has limited its spread. In recent years, advancements in therapeutic endoscopy have been made, and three major endoluminal alternatives are now available, including (1) the delivery of radiofrequency energy to the esophago-gastric junction, (2) transoral incisionless fundoplication (TIF), and (3) anti-reflux mucosal interventions (ARMI) based on mucosal resection (ARMS) and mucosal ablation (ARMA) techniques to remodel the cardia. Endoscopic techniques have shown interesting results, but their diffusion is still limited to expert endoscopists in tertiary centers. This review discusses the state of the art in the endoscopic approach to gastroesophageal reflux disease.

Indexed as

anti-reflux mucosal ablation (ARMA)anti-reflux mucosal interventions (ARMI)anti-reflux mucosal resection (ARMS)gastroesophageal reflux disease (GERD)transoral incisionless fundoplication (TIF)

Identifiers

PMID37370952
PMCPMC10297682
OpenAlexW4380997982

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.