Evidence map›Paper›PMID 37370901›Full record

ReviewDiagnostics (Basel, Switzerland)2023

Primary Benign Neoplasms of the Spine.

Sisith Ariyaratne, Nathan Jenko, Karthikeyan P Iyengar, Steven James, Jwalant Mehta, Rajesh Botchu

Open access · goldAbstract readReview
In one paragraph

Review in Diagnostics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Anatomy and Pathologies of the Spinous Process.Diseases (Basel, Switzerland) · 2024
    Review
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sisith AriyaratneDepartment of Musculoskeletal Radiology, Royal Orthopedic Hospital, Birmingham B31 2AP, UK.ORCID 0000-0002-7377-028X
Nathan JenkoDepartment of Musculoskeletal Radiology, Royal Orthopedic Hospital, Birmingham B31 2AP, UK.ORCID 0000-0003-2882-6923
Karthikeyan P IyengarDepartment of Orthopedics, Southport and Ormskirk Hospital NHS Trust, Southport PR8 6PN, UK.ORCID 0000-0002-4379-1266
Steven JamesDepartment of Musculoskeletal Radiology, Royal Orthopedic Hospital, Birmingham B31 2AP, UK.
Jwalant MehtaDepartment of Spinal Surgery, Royal Orthopedic Hospital, Birmingham B31 2AP, UK.
Rajesh BotchuDepartment of Musculoskeletal Radiology, Royal Orthopedic Hospital, Birmingham B31 2AP, UK.ORCID 0000-0001-7998-2980
Royal Orthopaedic Hospital · GBSouthport and Ormskirk Hospital NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign tumours comprise the majority of primary vertebral tumours, and these are often found incidentally on imaging. Nonetheless, accurate diagnosis of these benign lesions is crucial, in order to avoid misdiagnosis as more ominous malignant lesions or infection. Furthermore, some of these tumours, despite their benign nature, can have localised effects on the spine including neural compromise, or can be locally aggressive, thus necessitating active management. Haemangiomas and osteomas (enostosis) are the commonest benign tumours encountered. Others include osteoid osteoma, osteoblastoma, fibrous dysplasia, osteochondroma, chondroblastoma, haemangioma, simple bone cysts, aneurysmal bone cysts, giant cell tumours, eosinophilic granuloma and notochordal rests. The majority of lesions are asymptomatic; however, locally aggressive lesions (such as aneurysmal bone cysts or giant cell tumours) can present with nonspecific symptoms, such as back pain, neurological deficits and spinal instability, which may be indistinguishable from more commonly encountered mechanical back pain or malignant lesions including metastases. Hence, imaging, including radiography, computed tomography (CT) and magnetic resonance imaging (MRI), plays a critical role in diagnosis. Generally, most incidental or asymptomatic regions are conservatively managed or may not require any follow-up, while symptomatic or locally aggressive lesions warrant active interventions, which include surgical resection or percutaneous treatment techniques. Due to advances in interventional radiology techniques in recent years, percutaneous minimally invasive techniques such as radiofrequency ablation, sclerotherapy and cryoablation have played an increasing role in the management of these tumours with favourable outcomes. The different types of primary benign vertebral tumours will be discussed in this article with an emphasis on pertinent imaging features.

Indexed as

aneurysmal bone cystbenign primary vertebral tumourschondroblastomaCTeosinophilic granulomafibrous dysplasiagiant cell tumourhaemangiomaMRInotochordal restosteoblastomaosteochondromaosteoid osteomaosteomasimple bone cyst

Identifiers

PMID37370901
PMCPMC10297602
OpenAlexW4380082197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.