Evidence map›Paper›PMID 37370738›Full record

ArticleCancers2023

External-Beam-Accelerated Partial-Breast Irradiation Reduces Organ-at-Risk Doses Compared to Whole-Breast Irradiation after Breast-Conserving Surgery.

Oliver J Ott, Wilhelm Stillkrieg, Ulrike Lambrecht, Claudia Schweizer, Allison Lamrani, Tim-Oliver Sauer, Vratislav Strnad, Christoph Bert, Carolin C Hack, Matthias W Beckmann and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
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  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Oliver J OttDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.ORCID 0000-0001-5806-6158
Wilhelm StillkriegDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Ulrike LambrechtDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Claudia SchweizerDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.ORCID 0000-0002-1985-4116
Allison LamraniDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Tim-Oliver SauerDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Vratislav StrnadDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Christoph BertDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.ORCID 0000-0002-8539-6600
Carolin C HackComprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany.
Matthias W BeckmannComprehensive Cancer Center Erlangen-EMN, 91054 Erlangen, Germany.
Rainer FietkauDepartment of Radiation Oncology, Universitätsklinikum Erlangen, 91054 Erlangen, Germany.
Universitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In order to evaluate organ-at-risk (OAR) doses in external-beam-accelerated partial-breast irradiation (APBI) compared to standard whole-breast irradiation (WBI) after breast-conserving surgery. Between 2011 and 2021, 170 patients with early breast cancer received APBI within a prospective institutional single-arm trial. The prescribed dose to the planning treatment volume was 38 Gy in 10 fractions on 10 consecutive working days. OAR doses for the contralateral breast, the ipsilateral, contralateral, and whole lung, the whole heart, left ventricle (LV), and the left anterior descending coronary artery (LAD), and for the spinal cord and the skin were assessed and compared to a control group with real-world data from 116 patients who underwent WBI. The trial was registered at the German Clinical Trials Registry, DRKS-ID: DRKS00004417. Compared to WBI, APBI led to reduced OAR doses for the contralateral breast (0.4 ± 0.6 vs. 0.8 ± 0.9 Gy,

Indexed as

accelerated partial-breast irradiationbreast cancermean heart dosemean lung doseorgans-at-risk

Identifiers

PMID37370738
PMCPMC10296368
OpenAlexW4380090372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.