Evidence map›Paper›PMID 37370639›Full record

ArticleBioengineering (Basel, Switzerland)2023

OculusGraphy: Signal Analysis of the Electroretinogram in a Rabbit Model of Endophthalmitis Using Discrete and Continuous Wavelet Transforms.

Aleksei Zhdanov, Paul Constable, Sultan Mohammad Manjur, Anton Dolganov, Hugo F Posada-Quintero, Aleksander Lizunov

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Aleksei ZhdanovMachine Learning and Data Analytics Lab, University of Erlangen-Nuremberg, 91052 Erlangen, Germany.ORCID 0000-0003-4725-3681
Paul ConstableCollege of Nursing and Health Sciences, Caring Futures Institute, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0002-3994-1700
Sultan Mohammad ManjurDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.ORCID 0000-0001-6606-0493
Anton DolganovEngineering School of Information Technologies, Telecommunications and Control Systems, Ural Federal University Named after the First President of Russia B. N. Yeltsin, 620002 Yekaterinburg, Russia.ORCID 0000-0003-2318-9144
Hugo F Posada-QuinteroDepartment of Biomedical Engineering, University of Connecticut, Storrs, CT 06269, USA.ORCID 0000-0003-4514-4772
Aleksander LizunovDepartment of Functional Diagnostics, IRTC Eye Microsurgery Ekaterinburg Center, 620149 Yekaterinburg, Russia.ORCID 0000-0001-7019-3002
University of Connecticut · USUral Federal University · RUDagestan Center of Eye Microsurgery · RUFlinders University · AU

Funding

Ural Federal University Priority-2030 Program
6 · The paper itself

Abstract

backgroundThe electroretinogram is a clinical test used to assess the function of the photoreceptors and retinal circuits of various cells in the eye, with the recorded waveform being the result of the summated response of neural generators across the retina.

methodsThe present investigation involved an analysis of the electroretinogram waveform in both the time and time-frequency domains through the utilization of the discrete wavelet transform and continuous wavelet transform techniques. The primary aim of this study was to monitor and evaluate the effects of treatment in a New Zealand rabbit model of endophthalmitis via electroretinogram waveform analysis and to compare these with normal human electroretinograms.

resultsThe wavelet scalograms were analyzed using various mother wavelets, including the Daubechies, Ricker, Wavelet Biorthogonal 3.1 (bior3.1), Morlet, Haar, and Gaussian wavelets. Distinctive variances were identified in the wavelet scalograms between rabbit and human electroretinograms. The wavelet scalograms in the rabbit model of endophthalmitis showed recovery with treatment in parallel with the time-domain features.

conclusionsThe study compared adult, child, and rabbit electroretinogram responses using DWT and CWT, finding that adult signals had higher power than child signals, and that rabbit signals showed differences in the a-wave and b-wave depending on the type of response tested, while the Haar wavelet was found to be superior in visualizing frequency components in electrophysiological signals for following the treatment of endophthalmitis and may give additional outcome measures for the management of retinal disease.

Indexed as

biomedical researchelectrophysiologyelectroretinogramelectroretinographyERG

Identifiers

PMID37370639
PMCPMC10294831
OpenAlexW4380369417

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.