Evidence map›Paper›PMID 37370606›Full record

ArticleBioengineering (Basel, Switzerland)2023

Discovery and Characteristics of a Novel Antitumor Cyclopeptide Derived from Shark.

Fu Li, Minghua Lei, Junye Xie, Shujun Guo, Weicai Li, Xiujuan Ren, Teng Wang, Songxiong Lin, Qiuling Xie, Xiaojia Chen

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Fu LiDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.ORCID 0000-0003-2241-1196
Minghua LeiDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Junye XieDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-8925-524X
Shujun GuoDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Weicai LiDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Xiujuan RenDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Teng WangDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Songxiong LinGuangzhou Ocean Land Testing Technology Co., Ltd., Guangzhou 511400, China.
Qiuling XieDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.ORCID 0000-0002-0225-0260
Xiaojia ChenDepartment of Cell Biology, College of Life Science and Technology, Jinan University, Guangzhou 510632, China.
Jinan University · CN

Funding

Guangdong Provincial Key R&D Program 2022B1111070007National Natural Science Foundation of China NO. 82173729National Natural Science Foundation of China NO. 82273833Program of Department of Natural Resources of Guangdong Province GDNRC [2021] 50Science & Technology Program of Guangzhou City 20212210007Special Funds for the Cultivation of Guangdong College Students' Scientific and Technological Innovation pdjh2021a0051
6 · The paper itself

Abstract

Peptides pose a challenge in drug development due to their short half-lives in vivo. In this study, we conducted in vitro degradation experiments on SAIF, which is a shark-derived peptide that we previously studied. The degradation fragments were sequenced and a truncated peptide sequence was identified. The truncated peptide was then cloned and expressed via the

Indexed as

antitumorcyclopeptidelong-effectshark-derived

Identifiers

PMID37370606
PMCPMC10295666
OpenAlexW4379233394

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.