Evidence map›Paper›PMID 37370578›Full record

ArticleBioengineering (Basel, Switzerland)2023

Evaluation of Polymer-Coated Carbon Nanotube Flexible Microelectrodes for Biomedical Applications.

Chethani Ruhunage, Vaishnavi Dhawan, Chaminda P Nawarathne, Abdul Hoque, Xinyan Tracy Cui, Noe T Alvarez

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Chethani RuhunageDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0002-4709-5647
Vaishnavi DhawanDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0002-4710-2392
Chaminda P NawarathneDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0003-4760-463X
Abdul HoqueDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0002-2508-6811
Xinyan Tracy CuiDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0002-0470-2005
Noe T AlvarezDepartment of Chemistry, University of Cincinnati, Cincinnati, OH 45221, USA.ORCID 0000-0002-8392-1483

Funding

Development of carbon-nanotube fiber based microelectrode array for neuroscienceR21NS125461 · NINDS · UNIVERSITY OF CINCINNATI · PI ALVAREZ, NOE · 2022 to 2022
$431k
NIH HHS R21 NS125461-01NINDS NIH HHS R21 NS125461
6 · The paper itself

Abstract

The demand for electrically insulated microwires and microfibers in biomedical applications is rapidly increasing. Polymer protective coatings with high electrical resistivity, good chemical resistance, and a long shelf-life are critical to ensure continuous device operation during chronic applications. As soft and flexible electrodes can minimize mechanical mismatch between tissues and electronics, designs based on flexible conductive microfibers, such as carbon nanotube (CNT) fibers, and soft polymer insulation have been proposed. In this study, a continuous dip-coating approach was adopted to insulate meters-long CNT fibers with hydrogenated nitrile butadiene rubber (HNBR), a soft and rubbery insulating polymer. Using this method, 4.8 m long CNT fibers with diameters of 25-66 µm were continuously coated with HNBR without defects or interruptions. The coated CNT fibers were found to be uniform, pinhole free, and biocompatible. Furthermore, the HNBR coating had better high-temperature tolerance than conventional insulating materials. Microelectrodes prepared using the HNBR-coated CNT fibers exhibited stable electrochemical properties, with a specific impedance of 27.0 ± 9.4 MΩ µm

Indexed as

carbon nanotubesflexible polymer coatingshydrogenated nitrile butadiene rubberpinhole free polymer coatings

Identifiers

PMID37370578
PMCPMC10295676

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.