Evidence map›Paper›PMID 37370558›Full record

ArticleBioengineering (Basel, Switzerland)2023

The Digital Twin: A Potential Solution for the Personalized Diagnosis and Treatment of Musculoskeletal System Diseases.

Tianze Sun, Jinzuo Wang, Moran Suo, Xin Liu, Huagui Huang, Jing Zhang, Wentao Zhang, Zhonghai Li

Open access · goldAbstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 29 citations in OpenAlex.

  1. From patient notes to prognostication: The revolutionary potential of event-based foundation models in orthopaedics.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
    Article
  2. Review
  3. Artificial intelligence in orthopaedics: Enhanced examinations, ambient intelligence and the future of clinical practice.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Tianze SunDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China.ORCID 0000-0002-6646-1040
Jinzuo WangDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China.ORCID 0000-0002-9165-0716
Moran SuoDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China.
Xin LiuDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China.
Huagui HuangDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China.ORCID 0000-0002-5194-0671
Jing ZhangDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China.
Wentao ZhangDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China.
Zhonghai LiDepartment of Orthopedics, First Affiliated Hospital of Dalian Medical University, Dalian 116600, China.ORCID 0000-0003-4735-1193
Dalian Medical University · CN

Funding

the Natural Science Foundation of Liaoning Province 2022-MS-322the Science and Technology Innovation Foundation of Dalian 2022JJ12SN045
6 · The paper itself

Abstract

Due to the high prevalence and rates of disability associated with musculoskeletal system diseases, more thorough research into diagnosis, pathogenesis, and treatments is required. One of the key contributors to the emergence of diseases of the musculoskeletal system is thought to be changes in the biomechanics of the human musculoskeletal system. However, there are some defects concerning personal analysis or dynamic responses in current biomechanical research methodologies. Digital twin (DT) was initially an engineering concept that reflected the mirror image of a physical entity. With the application of medical image analysis and artificial intelligence (AI), it entered our lives and showed its potential to be further applied in the medical field. Consequently, we believe that DT can take a step towards personalized healthcare by guiding the design of industrial personalized healthcare systems. In this perspective article, we discuss the limitations of traditional biomechanical methods and the initial exploration of DT in musculoskeletal system diseases. We provide a new opinion that DT could be an effective solution for musculoskeletal system diseases in the future, which will help us analyze the real-time biomechanical properties of the musculoskeletal system and achieve personalized medicine.

Indexed as

AIbiomechanicsdigital twinmusculoskeletal systempersonalized medicine

Identifiers

PMID37370558
PMCPMC10295686
OpenAlexW4378078050

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.