Evidence map›Paper›PMID 37370477›Full record

ArticleAnimals : an open access journal from MDPI2023

An Intracellular Epitope of ASFV CD2v Protein Elicits Humoral and Cellular Immune Responses.

Wenlong Lu, Yilin Bai, Shuai Zhang, Xuyang Zhao, Jiaxin Jin, Xiaojing Zhu, Rui Wang, Yanan Wu, Angke Zhang, Gaiping Zhang and 2 more

Open access · goldAbstract read
In one paragraph

Article in Animals : an open access journal from MDPI, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Progress in African Swine Fever Vector Vaccine Development.International journal of molecular sciences · 2025
    Review
  8. The regulatory roles of STAT3 protein in the pathogenesis of viral infections.Frontiers in cellular and infection microbiology · 2025
    Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Wenlong LuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Yilin BaiLaboratory of Indigenous Cattle Germplasm Innovation, School of Agricultural Sciences, Zhengzhou University, Zhengzhou 450001, China.
Shuai ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0002-1217-6551
Xuyang ZhaoCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Jiaxin JinCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Xiaojing ZhuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Rui WangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Yanan WuCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Angke ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Gaiping ZhangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Guoqing ZhuangCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.ORCID 0000-0002-9460-4379
Aijun SunCollege of Veterinary Medicine, Henan Agricultural University, Zhengzhou 450046, China.
Henan Agricultural University · CNZhengzhou University · CN

Funding

Starting Foundation for Outstanding Young Scientists of Henan Agricultural University 30500690
6 · The paper itself

Abstract

The African swine fever virus (ASFV) causes high mortality in domestic pigs. ASFV encodes an important protein target for subunit vaccine development, CD2v, but its most effective immunological regions are not known. Herein, we generated a monoclonal antibody (mAb) named IF3 by immunizing mice against the intracellular region of the CD2v protein (CD2v-IR). 1F3 specifically recognized CD2v, which is expressed transiently in transfected Sf9 cells and also in inactivated ASFV-infected porcine alveolar macrophage (PAM) cells. The epitope recognized by 1F3 is

Indexed as

African swine fever virusCD2vepitopemonoclonal antibodyprokaryotic expressionvaccine

Identifiers

PMID37370477
PMCPMC10295607
OpenAlexW4380485659

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.