Evidence map›Paper›PMID 37370339›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Dynamics of Antibiotic Resistance of

Alexis Rybak, Corinne Levy, Naïm Ouldali, Stéphane Bonacorsi, Stéphane Béchet, Jean-François Delobbe, Christophe Batard, Isabelle Donikian, Marie Goldrey, Jessica Assouline and 2 more

Open access · goldAbstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
7.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Journal of preventive medicine and hygiene · 2026
    Article
  7. Global Antimicrobial Non-Susceptibility Patterns ofInfection and drug resistance · 2026
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Observational
  14. Article
  15. Characterization ofFrontiers in pediatrics · 2024
    Article
  16. Article
  17. Antibiotic Resistance ofAntibiotics (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Alexis RybakActiv, Association Clinique et Thérapeutique Infantile du Val-de-Marne, 94000 Créteil, France.ORCID 0000-0002-2898-3710
Corinne LevyActiv, Association Clinique et Thérapeutique Infantile du Val-de-Marne, 94000 Créteil, France.ORCID 0000-0002-1927-6360
Naïm OuldaliActiv, Association Clinique et Thérapeutique Infantile du Val-de-Marne, 94000 Créteil, France.
Stéphane BonacorsiMicrobiology Unit, Robert-Debré University Hospital, Assistance Publique-Hôpitaux de Paris, Université de Paris, 75019 Paris, France.
Stéphane BéchetActiv, Association Clinique et Thérapeutique Infantile du Val-de-Marne, 94000 Créteil, France.
Jean-François DelobbeAfpa, Association Française de Pédiatrie Ambulatoire, 45000 Orléans, France.
Christophe BatardActiv, Association Clinique et Thérapeutique Infantile du Val-de-Marne, 94000 Créteil, France.
Isabelle DonikianAfpa, Association Française de Pédiatrie Ambulatoire, 45000 Orléans, France.
Marie GoldreyAfpa, Association Française de Pédiatrie Ambulatoire, 45000 Orléans, France.
Jessica AssoulineAfpa, Association Française de Pédiatrie Ambulatoire, 45000 Orléans, France.
Robert CohenActiv, Association Clinique et Thérapeutique Infantile du Val-de-Marne, 94000 Créteil, France.ORCID 0000-0001-6151-0686
Emmanuelle VaronIMRB-GRC GEMINI, Institut Mondor de Recherche Biomédicale-Groupe de Recherche Clinique Groupe d'Etude des Maladie Infectieuses Néonatales et Infantiles, Université Paris Est, 94000 Créteil, France.ORCID 0000-0002-3043-2838
Association Française de Pédiatrie Ambulatoire · FRInserm · FRAssociation Clinique et Thérapeutique Infantile du Val de Marne · FRHôpital Intercommunal de Créteil · FRUniversité Paris Cité · FR

Funding

Pfizer (France) NA
6 · The paper itself

Abstract

Epidemiological surveillance of nasopharyngeal pneumococcal carriage is important for monitoring serotype distribution and antibiotic resistance, particularly before and after the implementation of pneumococcal conjugate vaccines (PCVs). With a prospective surveillance study in France, we aimed to analyze the dynamics of pneumococcal carriage, antibiotic susceptibility and serotype distribution in children aged 6 to 24 months who had acute otitis media between 2001 and 2022 with a focus on the late PCV13 period from May 2014 to July 2022. Trends were analyzed with segmented linear regression with autoregressive error. For the 17,136 children enrolled, overall pneumococcal carriage was stable during the study. During the late PCV13 period, the five most frequent serotypes were all non-PCV13 serotypes: 15B/C (14.3%), 23B (11.0%), 11A (9.6%), 15A (7.4%) and 35B (6.5%). During the same period, we observed a rebound of penicillin non-susceptibility (+0.15% per month, 95% confidence interval, +0.08 to 0.22,

Indexed as

acute otitis mediachildrennext-generation pneumococcal conjugate vaccinePCV impactpneumococcal nasopharyngeal carriagethird-generation pneumococcal conjugate vaccine

Identifiers

PMID37370339
PMCPMC10295685
OpenAlexW4379802425

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.