Evidence map›Paper›PMID 37370302›Full record

ArticleAntibiotics (Basel, Switzerland)2023

Adam O Whelan, Ian Cooper, Nicola Ooi, David Orr, Kevin Blades, James Kirkham, Amanda Lyons, Kay B Barnes, Mark I Richards, Anne-Marie Salisbury and 2 more

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Adam O WhelanDefence Science and Technology Laboratory, Porton Down, Salisbury SP4 0JQ, UK.
Ian CooperInfex Therapeutics Ltd., Mereside, Alderley Park, Macclesfield SK10 4TG, UK.
Nicola OoiInfex Therapeutics Ltd., Mereside, Alderley Park, Macclesfield SK10 4TG, UK.ORCID 0000-0002-6747-9699
David OrrInfex Therapeutics Ltd., Mereside, Alderley Park, Macclesfield SK10 4TG, UK.
Kevin BladesInfex Therapeutics Ltd., Mereside, Alderley Park, Macclesfield SK10 4TG, UK.
James KirkhamInfex Therapeutics Ltd., Mereside, Alderley Park, Macclesfield SK10 4TG, UK.
Amanda LyonsRedx Anti-Infectives Ltd., Alderley Park, Macclesfield SK10 4TG, UK.
Kay B BarnesDefence Science and Technology Laboratory, Porton Down, Salisbury SP4 0JQ, UK.
Mark I RichardsDefence Science and Technology Laboratory, Porton Down, Salisbury SP4 0JQ, UK.
Anne-Marie SalisburyRedx Anti-Infectives Ltd., Alderley Park, Macclesfield SK10 4TG, UK.
Mark CraigheadRedx Anti-Infectives Ltd., Alderley Park, Macclesfield SK10 4TG, UK.
Sarah V HardingDefence Science and Technology Laboratory, Porton Down, Salisbury SP4 0JQ, UK.

Funding

Ministry of Defence N/A
6 · The paper itself

Abstract

Antimicrobial resistance is a global issue, and the investigation of alternative therapies that are not traditional antibiotics are warranted. Novel bacterial type II topoisomerase inhibitors (NBTIs) have recently emerged as a novel class of antibiotics with reduced potential for cross-resistance to fluoroquinolones due to their novel mechanism of action. This study investigated the

Indexed as

biothreatBurkholderia pseudomalleiFrancisella tularensisin vitro activitytopoisomerase inhibitors

Identifiers

PMID37370302
PMCPMC10326817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.