Evidence map›Paper›PMID 37370050›Full record

Observational studyBMC pulmonary medicine2023

Health-related quality of life and radiological and functional lung changes of patients with COVID-19 Pneumonia 3 and 10 months after discharge.

Cristina De Juana, Susana Herrera, Silvia Ponce, Sergio Calvache, Loubna Dahmazi, Raffaele Vitale, Alberto José Ferrer, Verónica Valentín, Marta Acosta, Irene López and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC pulmonary medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Cristina De JuanaDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain. cristinadejui@gmail.com.
Susana HerreraDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain.
Silvia PonceDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain.
Sergio CalvacheDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain.
Loubna DahmaziDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain.
Raffaele VitaleUniversity of Lille, CNRS, LASIRE, Lille, France.
Alberto José FerrerPolytechnic University of Valencia, Valencia, Spain.
Verónica ValentínDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain.
Marta AcostaDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain.
Irene LópezDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain.
Eva Martínez-MoragónDepartment of Respiratory Medicine, Universitary Hospital Doctor Peset of Valencia, Valencia, Spain.
Respiratory medicine Unit of Universitary Hospital Doctor Peset of Valencia (Spain)
Hospital Universitario Doctor Peset · ESCentre National de la Recherche Scientifique · FRUniversitat Politècnica de València · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew studies have evaluated the long-term impact on health-related quality of life (HRQoL) in patients who have been hospitalized for COVID-19 pneumonia. Specific follow-up should be carried out to detect and treat possible pulmonary abnormalities, and the worsening of HRQoL should be estimated to target necessary resources for care of these patients after acute phase. The objective was to know the impact on HRQoL of patients who have been admitted for COVID-19 pneumonia, and to evaluate the clinical-radiological and functional changes of patients who have overcome COVID-19 pneumonia at 3 and 10 months of follow-up.

methodsProspective observational study of patients who required hospitalization for COVID-19 pneumonia between April and December 2020. All patients filled out the EuroQol five-dimension (EQ-5D) questionnaire with the EuroQol Visual Analogue Scale (E-VAS) for self-assessment of health status. Respiratory function tests and chest X-ray were carried out at 3 and 10 months of follow-up.

results61 patients were included in the study. The need for ventilatory support was associated with anxiety/depression on the EQ-5D scale, as well as patients admitted to the intensive care unit (ICU). The mean EQ-5D and E-VAS index scores decreased with hospitalization time, the number of days spent in intermediate respiratory care unit (IRCU) and the level of dyspnoea at the beginning of the hospitalization period. Pulmonary sequelae were observed in 25 patients (41%) at 3 months and 17 (27.9%) at 10 months. Patients improve their forced vital capacity (FVC) by 196 ml (p = 0.001) at 10 months as well as 9% in diffusing capacity of lung for carbon monoxide (DLCO) (p = 0.001) at 10 months. DLCO was found to be correlated to lymphopenia and time spent in IRCU. Low FVC values were detected 10 months after discharge for subjects exhibiting high levels of dyspnoea at 3 months after discharge.

conclusionsHospitalization for COVID-19 pneumonia affects the HRQoL of patients, with greater anxiety/depression in those who were more serious affected and are younger. A significant percentage of patients present fibrotic abnormalities and lung function impairment at the first and second follow-up after discharge.

Indexed as

COVID-19Quality of LifeDyspneaHumansLungPatient DischargeCOVID-19Follow-up radiological findings and pulmonary functionHealth-related quality of life

Identifiers

PMID37370050
PMCPMC10303856
OpenAlexW4382196741

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.