Evidence map›Paper›PMID 37369816›Full record

ArticleClinical oral investigations2023

Effects of experimental bleaching gels containing co-doped titanium dioxide and niobium pentoxide combined with violet light.

Iago César Ribeiro Teles Matos, Matheus Kury, Priscila Borges Gobbo de Melo, Leticia Vasconcelos Silva de Souza, Fernando Luis Esteban Florez, Vanessa Cavalli

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06802614 (A Randomized Controlled Clinical Trial Comparing the Efficacy of Two Experimental Bleaching Gels With and Without Nanoparticles and Light Irradiation Versus Whiteness HP 35% and Whiteness HP AutoMixx 6% in Patients With A2-C4 Tooth Discolorations), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06802614 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Randomized Controlled Clinical Trial Comparing the Efficacy of Two Experimental Bleaching Gels With and Without Nanoparticles and Light Irradiation Versus Whiteness HP 35% and Whiteness HP AutoMixx 6% in Patients With A2-C4 Tooth Discolorations

TypeinterventionalSponsorUniversity of OklahomaRan2025 to 2025Enrolled240ConditionsTooth Discoloration, Dentin Sensitivity, Patient SatisfactionArmsBLEACHING GEL A, 5% NF_TiO2, BLEACHING GEL B, VISIBLE LIGHT IRRADIATION, Whiteness HP 35%
3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Hyaluronic Acid-Based Bleaching Gels With NF_TiOJournal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Article
  5. Assessing the Impact of Vegan Toothpastes on Enamel Color Change and Surface Properties.Journal of esthetic and restorative dentistry : official publication of the American Academy of Esthetic Dentistry ... [et al.] · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Iago César Ribeiro Teles MatosDivision of Operative Dentistry, Department of Restorative Dentistry, Piracicaba School of Dentistry, University of Campinas, Piracicaba, SP, Brazil.
Matheus KuryDivision of Operative Dentistry, Department of Restorative Dentistry, Piracicaba School of Dentistry, University of Campinas, Piracicaba, SP, Brazil.
Priscila Borges Gobbo de MeloDivision of Operative Dentistry, Department of Restorative Dentistry, Piracicaba School of Dentistry, University of Campinas, Piracicaba, SP, Brazil.
Leticia Vasconcelos Silva de SouzaDivision of Operative Dentistry, Department of Restorative Dentistry, Piracicaba School of Dentistry, University of Campinas, Piracicaba, SP, Brazil.
Fernando Luis Esteban FlorezDivision of Dental Biomaterials, Department of Restorative Sciences, University of Oklahoma Health Sciences Center College of Dentistry, Oklahoma City, OK, USA.
Vanessa CavalliDivision of Operative Dentistry, Department of Restorative Dentistry, Piracicaba Dental School, University of Campinas, 901 Limeira Av., Piracicaba, SP, Brazil. cavalli@unicamp.br.

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 001
6 · The paper itself

Abstract

objectivesThe objective of the study is to evaluate the bleaching potential of 6% hydrogen peroxide (6% HP) gels containing NF_TiO

methodsParticles were synthesized, and experimental gels were chemically analyzed by preliminary and accelerated stability tests, pH, and HP decomposition rate. Bovine enamel blocks were treated with 6% HP gels containing (n = 10): 5% NF_TiO

resultsNo changes in the gel's color, odor, or translucency were observed. The pH (6 to 6.5) remained stable over time, and light irradiation boosted the HP decomposition rate. NF_TiO

conclusionExperimental light-irradiated 6% HP gels containing NF_TiO CLINICAL RELEVANCE: Low-concentrated HP gels containing NF_TiO

Indexed as

Tooth BleachingTooth Bleaching AgentsAnimalsCattleGelsHydrogen PeroxideHypochlorous AcidNiobiumOxidesTitaniumGelsHydrogen PeroxideHypochlorous AcidNiobiumniobium pentoxideOxidesTitaniumtitanium dioxideTooth Bleaching AgentsBleaching agentsNanoparticlesNiobiumTitaniumTooth whitening

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.