ArticleBurns : journal of the International Society for Burn Injuries2023
Early wound excision within three days decreases risks of wound infection and death in burned patients.
Article in Burns : journal of the International Society for Burn Injuries, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 22 citations in OpenAlex.
- Sequential Bromelain-Based Enzymatic Debridement in a Near-Total (97%) TBSA Burn: A Case Report.European burn journal · 2026Article
- Infections in Burn Patients: Pathophysiology, Prevention, and Contemporary Therapeutic Strategies in the Era of Antimicrobial Resistance.Infectious diseases and therapy · 2026Review
- The Impact of Concomitant Traumatic Brain Injuries on the Surgical Treatment of Burns: A Long-Term, Monocentric Retrospective Study.Journal of burn care & research : official publication of the American Burn Association · 2026Article
- What is new in burn shock resuscitation?Intensive care medicine · 2025Article
- Two Cases of Enzymatic Debridement for Deep Burn Wounds Associated with Automobile Run-over Injuries.Journal of plastic and reconstructive surgery · 2025Article
- Burn Progression in Human Skin-A Review of Current Knowledge and Opportunities for Future Research.Journal of burn care & research : official publication of the American Burn Association · 2025Review
- Fungal infections in burn patients: The rise of Fusarium as the most prevalent in a burn center in Mexico City.Medical mycology · 2025Article
- Hypertrophic and Keloid Scar Management: Advances in Diagnosis, Perioperative Care, and Anesthetic Modulation.Cureus · 2025Review
- Pig Model to Test Tissue Engineered Skin.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Epidemiology and timing of infectious complications from battlefield-related burn injuries.Burns : journal of the International Society for Burn Injuries · 2024Article
- A Pilot Analysis for a Multicentric, Retrospective Study on Biodiversity and Difficult-to-Treat Pathogens in Burn Centers across the United States (MICROBE).Pathogens (Basel, Switzerland) · 2024Article
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
Abstract
introductionIn lieu of limited studies on the timing of burn wound eschar excision for burns, a more comprehensive analysis is indicated to determine the effects of early wound excision following burns. This study aims to address the outcomes of early wound excision in burn patients.
methodsData collection were from TriNetX research database. Three groups of burn patients were stratified by the number of days in which they received burn wound excision within 14 days of injury. Five outcomes were observed: death, wound infection, sepsis, myocardial contractile dysfunction, and blood transfusion. Risk and incidence of various health outcomes were compared between the groups after propensity-matching age, sex, ethnicity, race and burn size using a z-test with p < 0.05 considered significant.
resultsWe identified 6158 burn patients with wound excision within 14 days of injury, the majority of whom (60.1%) received burn wound excision between 0 and 3 days after burn. 72.5% of patients had burns covering less than 20% of total body surface area. After propensity matching, we found a significantly lower risk of mortality in those who received burn wound excision within the first three days (3.84%) as compared to 8-14 days after burn (6.09%) (p < 0.05). Moreover, we found a decreased risk of wound infection in patients with burn wound excision within 0-3 days (37.84%) compared to those 4-7 days (42.48%) (p < 0.05). No statistical difference was detected in propensity-matched groups for myocardial contractile dysfunction, blood transfusion, or sepsis. In addition, the risk of hypertrophic scaring significantly decreased when wound excision was performed within 0-3 days (22% within 0-3 days, 28% within 4-7 days, p < 0.05).
conclusionBurn wound excision within 3 days of injury is beneficial when comparing to later treatment between 4 and 14 days, which results in a significantly lowered risk of mortality and infection in burn patient.
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