Evidence map›Paper›PMID 37369498›Full record

ArticleIn vivo (Athens, Greece)

Effect of the Mediterranean Diet on Progression of Dry Form of Age-related Macular Degeneration.

Danai-Magdalini Gourgouli, Ioanna Gourgouli, Sofia Spai, Kalliopi Gourgouli, Evangelia Tzorovili, Maria Skouroliakou, Dimitrios Papakonstantinou, Marilita M Moschos

Open access · diamondAbstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Danai-Magdalini GourgouliFirst Department of Ophthalmology, National and Kapodistrian University of Athens, "G. Gennimatas" General Hospital of Athens, Athens, Greece; danaigou13@yahoo.com.
Ioanna GourgouliDepartment of Ophthalmology, "Sismanoglio" General Hospital of Athens, Athens, Greece.
Sofia SpaiDepartment of Ophthalmology, "Sismanoglio" General Hospital of Athens, Athens, Greece.
Kalliopi GourgouliDivision of Genetics and Biotechnology, Department of Biology, National and Kapodistrian University of Athens, Athens, Greece.
Evangelia TzoroviliFortrea Development LTD, Athens, Greece.
Maria SkouroliakouDepartment of Nutrition and Dietetics, Harokopio University of Athens, Athens, Greece.
Dimitrios PapakonstantinouFirst Department of Ophthalmology, National and Kapodistrian University of Athens, "G. Gennimatas" General Hospital of Athens, Athens, Greece.
Marilita M MoschosFirst Department of Ophthalmology, National and Kapodistrian University of Athens, "G. Gennimatas" General Hospital of Athens, Athens, Greece; moschosmarilita@yahoo.fr.
General Hospital of Athens G. Genimatas · GRNational and Kapodistrian University of Athens · GRSismanoglio General Hospital · GRHarokopio University of Athens · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe aim of this study was to investigate the possible effect of the Mediterranean diet (Med Diet) on the progression of age-related macular degeneration (AMD) in patients with early or intermediate stages of dry AMD. PATIENTS AND

methodsThe present study included 164 patients with early or intermediate dry AMD. Data collected included demographics, anthropometric data, ophthalmic and medical history. AMD progression was evaluated using patients' optical coherence tomography (OCT) and visual acuity. Using the MedDietScore, sample's attachment to Med Diet was evaluated, and distinguished into high and low. The association of supplement intake and adherence to Med Diet with AMD progression was investigated using logistic regression.

resultsSample's mean age was 73±7.4 years. A positive correlation was found between dietary supplementation and slowing of AMD progression, as well as between high adherence to Med Diet and slowing of AMD progression. In contrast, smokers had 51.4% higher risk of AMD progression (p=0.043). The rate of slowing AMD progression was higher in patients who followed Med Diet and received a dietary supplement, compared to patients who followed one or none of the aforementioned recommendations (p<0.001).

conclusionAdherence to the Med Diet could have a positive effect on delaying AMD progression in advanced stages, both in patients receiving or not antioxidants. Therefore, our study proposes to strengthen recommendations to AMD patients to follow a Med Diet.

Indexed as

Dietary SupplementsDiet, MediterraneanMacular DegenerationAgedAged, 80 and overDisease ProgressionFemaleHumansMaleTomography, Optical CoherenceVisual Acuityage-related macular degeneration (AMD)dietary supplementdry AMDluteinMediterranean dietzeaxanthin

Identifiers

PMID37369498
PMCPMC10347925
OpenAlexW4382344502

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.