ArticleIn vivo (Athens, Greece)
Impact of Advanced Maternal Age on Maternal and Neonatal Outcomes.
Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 20 citations in OpenAlex.
- Influence of advanced maternal age (≥35 years) on maternal and neonatal outcomes in vaginally intended breech deliveries at term-A FRABAT study.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Age-Dependent Alterations of Chromosomal Passenger Complex Members During Implantation and Decidualization in the Mouse Uterus.Aging cell · 2026Article
- Effect of advanced maternal age on the risk of adverse birth outcomes: a retrospective cohort study.BMC pregnancy and childbirth · 2025Article
- Postponed childbearing: a cross-sectional study of differences between subjective and objective factors.Annals of medicine · 2025Article
- Risk Profiles and Outcomes of Uterine Rupture: A Retrospective and Comparative Single-Center Study of Complete and Partial Ruptures.Journal of clinical medicine · 2025Article
- Application of Chromosomal Karyotype Analysis Combined With Chromosomal Microarray Analysis in the Amniotic Fluid of Advanced Maternal Age.Journal of clinical laboratory analysis · 2025Article
- Delaying Motherhood-An Increasingly Common but Risky Trend in High-Income Countries.American journal of human biology : the official journal of the Human Biology Council · 2025Article
- Impact of maternal age on birth weight-related adverse outcomes in newborns: a retrospective study in south-central China.BMC pregnancy and childbirth · 2025Article
- Analysis of the influence of advanced maternal age on gestational and fetal outcomes.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2025Observational
- Antenatal Perineal Training for Injuries Prevention: Follow Up after Puerperium.Medicina (Kaunas, Lithuania) · 2024Article
- Uterine Aging and Reproduction: Dealing with a Puzzle Biologic Topic.International journal of molecular sciences · 2023Review
- Dose-response associations of maternal age with pregnancy complications and multimorbidity among nulliparas and multiparas: A multicentric retrospective cohort study in southern China.Journal of global health · 2023Article
- Pregnancy Outcomes FollowingIn vivo (Athens, Greece)Article
- Maternal and Perinatal Outcome After Induction of LaborIn vivo (Athens, Greece)Article
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND/
aimDue to better career opportunities for women and a shift in sex roles, as well as improved reproductive medicine, the age of women who conceive children is rising. A variety of maternal risks and complications that may occur during pregnancy or childbirth in women with advanced maternal age has been examined and reported controversial results. The present study focused on controversial and debatable conclusions regarding the impact of advanced maternal age on maternal and neonatal outcomes. PATIENTS AND
methodsData from 8,523 patients, who gave singleton birth at the Women's University Hospital Cologne between 2014 and 2018, were subdivided into two groups: those with maternal age ≥40 years and those <40, and analyzed.
resultsA significantly higher rate of C-section, more preterm births, more low birth weight, and higher incidence of retained placenta were observed in women older than or equal to 40. There were no significant differences regarding postpartum hemorrhage and fetal position. Younger patients tend to have more birth injuries and use more epidural administration. The evaluation of neonatal outcomes using fetal base-excess, birth pH, and Apgar score showed no significant clinical differences.
conclusionMore antenatal complications could be identified in patients with advanced maternal age. Nonetheless, the neonatal outcomes were comparable and no severe complications in women with advanced maternal age were observed. These findings are due to a well standardized management system for women with risk pregnancies. This encourages better monitoring and care of pregnant women with risk factors.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.