Evidence map›Paper›PMID 37369415›Full record

Observational studyBMJ open2023

Unmet vaccination need among children under the age of five attending the paediatric emergency department: a cross-sectional study in a large UK district general hospital.

Rachel Isba, Louise Brennan, Fiona Egboko, Rhiannon Edge, Nigel Davies, Joanne Knight

Registry-linked trialOpen access · goldAbstract readObservational Study
In one paragraph

Observational study in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04485624 (Do Children and Young People Attending the Paediatric Emergency Department Have Lower Levels of Vaccination Coverage Than Their Peers in the Local General Population?), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04485624 completednot on this map

Do Children and Young People Attending the Paediatric Emergency Department Have Lower Levels of Vaccination Coverage Than Their Peers in the Local General Population?

TypeobservationalSponsorLancaster UniversityRan2021 to 2021Enrolled2,693ConditionsVaccination/Immunisation StatusArmsNo intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Rachel IsbaLancaster University, Lancaster, UK rachel.isba@lancaster.ac.uk.ORCID 0000-0002-2896-4309
Louise BrennanLancaster University, Lancaster, UK.ORCID 0000-0003-0377-6720
Fiona EgbokoLancaster University, Lancaster, UK.
Rhiannon EdgeLancaster University, Lancaster, UK.ORCID 0000-0001-5349-783X
Nigel DaviesLancaster University, Lancaster, UK.ORCID 0000-0002-4136-5300
Joanne KnightLancaster University, Lancaster, UK.ORCID 0000-0002-7148-1660
Lancaster University · GBNorth Manchester General Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate vaccination coverage among children under the age of five attending the paediatric emergency department (PED) using tetanus and MMR vaccination as a proxy.

designA cross-sectional observational study with a single data collection point for each participant.

settingA single large PED in Greater Manchester, England.

participantsChildren (under 5 years old) attending the PED during October 2021. Participation was 'opt-out' and parents/carers were given until the end of the following month to request that their child's data be excluded. PRIMARY AND SECONDARY OUTCOME MEASURES: The primary outcome of interest was the percentage of children who were up-to-date with their routine childhood vaccinations at their time of attendance to the PED. Secondary outcome measures were the percentage of children who had received age-appropriate tetanus and MMR vaccination, and how these compared with local population data at the ages of 1, 2 and 5 years of age.

resultsOne-third of under-5s in this study had unmet vaccination need and were missing at least one dose of either MMR or tetanus-containing vaccine. In older age groups, many were missing their tetanus boosters and only 1 in 5 of those eligible had received two doses of MMR. Those in younger age groups had vaccination coverage levels comparable to the local data, but still below the target of 95%.

conclusionsThose children eligible for preschool boosters (tetanus and MMR2) appear to have considerable unmet vaccination need. While the pandemic has had an impact, the observation that MMR2 uptake is considerably lower than tetanus booster (when they are scheduled together) warrants further investigation. Catch-up campaigns for MMR2 should focus on this cohort of children and the PED may offer an opportunity for an intervention. TRIAL REGISTRATION NUMBER: NCT04485624.

Indexed as

TetanusAgedChildChild, PreschoolCross-Sectional StudiesEnglandHospitals, GeneralHumansImmunization, SecondaryTetanus ToxoidVaccinationTetanus ToxoidPaediatric infectious disease & immunisationPublic health

Identifiers

PMID37369415
PMCPMC10410832
OpenAlexW4382344456

What OpenQuestion holds

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LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.