Evidence map›Paper›PMID 37369411›Full record

ArticleBMJ open2023

Adverse birth outcome case definitions associated with maternal HIV and antiretroviral drug use in pregnancy: a scoping review protocol.

Kopano Rebaona Dube, Kathleen M Powis, Michael McCaul, Shani Tamlyn de Beer, Amy L Slogrove

Abstract read
In one paragraph

Article in BMJ open, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kopano Rebaona DubeDeparmtment of Paediatrics & Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, Western Cape, South Africa.ORCID 0000-0002-6609-3516
Kathleen M PowisDeparment of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Michael McCaulDivision of Epidemiology and Biostatistics, Department of Global Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, Western Cape, South Africa.
Shani Tamlyn de BeerCentre for Infectious Disease Epidemiology and Research, Faculty of Health Sciences University of Cape Town, Cape Town, Western Cape, South Africa.
Amy L SlogroveDeparmtment of Paediatrics & Child Health, Stellenbosch University Faculty of Medicine and Health Sciences, Cape Town, Western Cape, South Africa amy@sun.ac.za.ORCID 0000-0002-8046-9268

Funding

CHERISH (Children HIV Exposed Uninfected Research to Inform Survival and Health)R33HD103093 · NICHD · STELLENBOSCH UNIVERSITY · PI DAVIES, MARY-ANN, TOMLINSON, MARK · 2023 to 2025
$1.5M
The effect of hypertensive disorders in pregnancy and HIV-infection on maternal, birth and infant outcomes in South AfricaK43TW010683 · FIC · STELLENBOSCH UNIVERSITY · PI SLOGROVE, AMY LOUISE · 2017 to 2021
$647k
FIC NIH HHS K43 TW010683NICHD NIH HHS R33 HD103093
6 · The paper itself

Abstract

introductionThe global antiretroviral therapy era has led to a decline in the number of children newly acquiring HIV and an increase in the number of children who are HIV-exposed and uninfected (HEU). This shift has prompted extensive research focussing on health and survival outcomes of children who are HEU. Study findings, particularly in relation to adverse birth outcomes, have been disparate, inconclusive and have not always been generalisable. Thus, the objectives of this scoping review are (1) to identify and extract definitions used for the adverse birth outcome terms 'low birth weight', 'small for gestational age', 'stillbirth' and 'preterm birth'; (2) to compare the characteristics of studies from which birth outcome definitions were extracted by (a) temporal periods and (b) study country setting (high-income vs low-income and middle-income countries); (3) to use content analysis to map and describe the temporal and geographic distribution of the definitions used and construct a logical model of their evolution. METHODS AND ANALYSIS: The online databases of PubMed/MEDLINE, Scopus, Web of Science, Cochrane Library and CINHAL/EBSCOhost will be used to identify published and grey literature from 2011 to 2022 to identify definitions for the adverse birth outcome terms 'low birth weight', 'small for gestational age', 'stillbirth' and 'preterm birth'. A three-step process of (1) duplicate removal, (2) title and abstract screening and (3) full text screening will be used to select included studies. The extracted data will be used to conduct a comparative analysis, content analysis and construct a logic model. ETHICS AND DISSEMINATION: This review will be used to inform a consensus process around the development of harmonised definitions for the specified adverse birth outcomes. Our dissemination plan includes presentations, publications as well as the development infographics and a resource hub. The study is approved by the Human Research Ethics Committee of Stellenbosch University.

Indexed as

HIV InfectionsPregnancy ComplicationsPremature BirthAnti-Retroviral AgentsBirth WeightChildFemaleHumansInfant, NewbornPregnancyPregnancy OutcomeScoping Reviews as TopicStillbirthAnti-Retroviral AgentsHIV & AIDSMaternal medicinePAEDIATRICS

Identifiers

PMID37369411
PMCPMC10410838

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.