Evidence map›Paper›PMID 37369003›Full record

ArticleACS chemical neuroscience2023

Dexamethasone-Enhanced Continuous Online Microdialysis for Neuromonitoring of O

Elaine M Robbins, Andrea S Jaquins-Gerstl, David O Okonkwo, Martyn G Boutelle, Adrian C Michael

Open access · hybridAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Elaine M RobbinsDepartment of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 15260, United States.
Andrea S Jaquins-GerstlDepartment of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 15260, United States.
David O OkonkwoDepartment of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, United States.
Martyn G BoutelleDepartment of Bioengineering, Imperial College London, London SW7 2AZ, United Kingdom.ORCID 0000-0003-1332-3442
Adrian C MichaelDepartment of Chemistry, University of Pittsburgh, 219 Parkman Avenue, Pittsburgh, Pennsylvania 15260, United States.ORCID 0000-0001-9069-4664
University of Pittsburgh · USImperial College London · GB

Funding

Enhanced Bedside Microdialysis for TBIR01NS102725 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MICHAEL, ADRIAN C, PUCCIO, AVA M. · 2018 to 2022
$2.7M
Technical enhancements for intracranial microdialysisR21NS109875 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MICHAEL, ADRIAN C · 2018 to 2019
$401k
NINDS NIH HHS R01 NS102725NINDS NIH HHS R21 NS109875
6 · The paper itself

Abstract

Traumatic brain injury (TBI) is a major public health crisis in many regions of the world. Severe TBI may cause a primary brain lesion with a surrounding penumbra of tissue that is vulnerable to secondary injury. Secondary injury presents as progressive expansion of the lesion, possibly leading to severe disability, a persistent vegetive state, or death. Real time neuromonitoring to detect and monitor secondary injury is urgently needed. Dexamethasone-enhanced continuous online microdialysis (Dex-enhanced coMD) is an emerging paradigm for chronic neuromonitoring after brain injury. The present study employed Dex-enhanced coMD to monitor brain K

Indexed as

Brain InjuriesBrain Injuries, TraumaticAnimalsBrainDexamethasoneMicrodialysisRatsDexamethasonecontrolled cortical impactdexamethasoneMicrodialysisoxygenspreading depolarizationtraumatic brain injury

Identifiers

PMID37369003
PMCPMC10360069
OpenAlexW4382344116

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.