Evidence map›Paper›PMID 37368715›Full record

ArticleTropical medicine and infectious disease2023

Chagas Disease: Medical and ECG Related Findings in an Indigenous Population in Colombia.

Simone Kann, Gustavo Andrés Concha Mendoza, Maria Hartmann, Hagen Frickmann, Lothar Kreienbrock

Open access · goldAbstract read
In one paragraph

Article in Tropical medicine and infectious disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Chagas Disease Control-Many Approaches to Prospect.Tropical medicine and infectious disease · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Simone KannMedmissio, 97074 Wuerzburg, Germany.
Gustavo Andrés Concha MendozaOrganisation Wiwa Yugumaiun Bunkuanarrua Tayrona (OWYBT), Valledupar 200001, Colombia.
Maria HartmannDepartment of Biometry, Epidemiology and Information Processing, WHO Collaborating Centre for Research and Training for Health in the Human-Animal-Environment Interface, University for Veterinary Medicine Hannover, 30559 Hannover, Germany.ORCID 0000-0002-3567-7869
Hagen FrickmannInstitute for Medical Microbiology, Virology and Hygiene, University Medicine Rostock, 18057 Rostock, Germany.ORCID 0000-0002-8967-9528
Lothar KreienbrockDepartment of Biometry, Epidemiology and Information Processing, WHO Collaborating Centre for Research and Training for Health in the Human-Animal-Environment Interface, University for Veterinary Medicine Hannover, 30559 Hannover, Germany.
University of Veterinary Medicine Hannover, Foundation · DEBundeswehrkrankenhaus · DE

Funding

Else Kröner-Fresenius-Stiftung 2019_HA163
6 · The paper itself

Abstract

Chagas Disease (CD) is highly prevalent among the indigenous populations in the Sierra Nevada de Santa Marta, Colombia. Villages examined show prevalence rates ranging from 43.6% up to 67.4%. In the present study, associated medical conditions were assessed with a particular focus on ECG alterations. CD diagnosis was based on a rapid test, two different ELISAs, and a specific and highly sensitive Chagas real-time PCR. In both CD positive and CD negative patients, relations of the status and medical (physical examination-based, questionnaire-based) and/or electrocardiogram-based findings were investigated. As expected, CD-associated symptoms and complaints were predominantly found in CD-positive patients. Interestingly, ECG-findings were found to show the potential of leading to early CD diagnosis because ECG alterations were already seen in early stagechanges of the disease. In conclusion, although the observed ECG changes are unspecific, they should be considered as an indicator for a CD screening and, in case of positive results, an associated early treatment of the disease.

Indexed as

cardiomyopathyChagas diseaserhythm disturbancessudden heart death

Identifiers

PMID37368715
PMCPMC10301814
OpenAlexW4378714742

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.