Evidence map›Paper›PMID 37368683›Full record

ArticleToxins2023

Safety and Effectiveness of Repeated Botulinum Toxin A Intracavernosal Injections in Men with Erectile Dysfunction Unresponsive to Approved Pharmacological Treatments: Real-World Observational Data.

François Giuliano, Pierre Denys, Charles Joussain

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Toxins, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07537855 (Clinical Efficacy of Intracavernosal Xeomin as an Adjunctive Therapy to on Demand Tadalafil 20 mg for the Treatment of Mild to Moderate Erectile Dysfunction), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07537855 phase2not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Clinical Efficacy of Intracavernosal Xeomin as an Adjunctive Therapy to on Demand Tadalafil 20 mg for the Treatment of Mild to Moderate Erectile Dysfunction: A Randomized Crossover Pilot Study

TypeinterventionalSponsorNorthwestern UniversityRan2026 to 2028Enrolled30ConditionsErectile DysfunctionArmsIncobotulinumtoxinA (100 Units), Placebo, Tadalafil 20 MG
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Pooled it
  2. Neuroscience in prostate cancer.Prostate cancer and prostatic diseases · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

François GiulianoNeuro-Uro-Andrology R. Poincare University Hospital, AP-HP, 104 Bvd R. Poincare, 92380 Garches, France.
Pierre DenysNeuro-Uro-Andrology R. Poincare University Hospital, AP-HP, 104 Bvd R. Poincare, 92380 Garches, France.ORCID 0000-0002-4831-6499
Charles JoussainNeuro-Uro-Andrology R. Poincare University Hospital, AP-HP, 104 Bvd R. Poincare, 92380 Garches, France.
Inserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intracavernosal injections of botulinum toxin A (BTX/A

Indexed as

Botulinum Toxins, Type AErectile DysfunctionAlprostadilHumansMalePenile ErectionPhosphodiesterase 5 InhibitorsRetrospective StudiesTreatment OutcomeAlprostadilBotulinum Toxins, Type APhosphodiesterase 5 InhibitorsabobotulinumtoxinAincobotulinumtoxinA phosphodiesterase type 5 inhibitorsonabotulinumtoxinAprostaglandinE1

Identifiers

PMID37368683
PMCPMC10301648
OpenAlexW4379473265

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.