Evidence map›Paper›PMID 37368632›Full record

ArticleToxics2023

Comparable Response Following Exposure to Biodiesel and Diesel Exhaust Particles in Advanced Multicellular Human Lung Models.

Mizanur Rahman, Swapna Upadhyay, Koustav Ganguly, Micol Introna, Jie Ji, Christoffer Boman, Ala Muala, Anders Blomberg, Thomas Sandström, Lena Palmberg

Open access · goldAbstract read
In one paragraph

Article in Toxics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 19 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Mizanur RahmanUnit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.
Swapna UpadhyayUnit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.
Koustav GangulyUnit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0001-8531-8154
Micol IntronaUnit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.
Jie JiUnit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.
Christoffer BomanThermochemical Energy Conversion Laboratory, Department of Applied Physics and Electronics, Umeå University, 901 87 Umeå, Sweden.ORCID 0000-0003-4428-3201
Ala MualaDepartment of Public Health and Clinical Medicine, Umeå University, 901 87 Umeå, Sweden.ORCID 0009-0009-2345-7584
Anders BlombergDepartment of Public Health and Clinical Medicine, Umeå University, 901 87 Umeå, Sweden.
Thomas SandströmDepartment of Public Health and Clinical Medicine, Umeå University, 901 87 Umeå, Sweden.
Lena PalmbergUnit of Integrative Toxicology, Institute of Environmental Medicine, Karolinska Institutet, 171 77 Stockholm, Sweden.
Karolinska Institutet · SEUmeå University · SE

Funding

The Swedish Research Council (LP: 2018-03233)
6 · The paper itself

Abstract

Biodiesel is considered to be a sustainable alternative for fossil fuels such as petroleum-based diesel. However, we still lack knowledge about the impact of biodiesel emissions on humans, as airways and lungs are the primary target organs of inhaled toxicants. This study investigated the effect of exhaust particles from well-characterized rapeseed methyl ester (RME) biodiesel exhaust particles (BDEP) and petro-diesel exhaust particles (DEP) on primary bronchial epithelial cells (PBEC) and macrophages (MQ). The advanced multicellular physiologically relevant bronchial mucosa models were developed using human primary bronchial epithelial cells (PBEC) cultured at air-liquid interface (ALI) in the presence or absence of THP-1 cell-derived macrophages (MQ). The experimental set-up used for BDEP and DEP exposures (18 µg/cm

Indexed as

biodieselCOX-2DNA damagelungMQ-ALIoxidative stressparticlesPBEC-ALIpetro-dieselPGE2phagocytosis

Identifiers

PMID37368632
PMCPMC10304096
OpenAlexW4380996704

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.