Evidence map›Paper›PMID 37368202›Full record

ArticleDigestive diseases and sciences2023

Influence of Frailty in Patients Undergoing Endoscopic Retrograde Cholangiopancreatography for Biliary Stone Disease: A Nationwide Study.

Daryl Ramai, Joseph Heaton, Andrew Ofosu, Paraskevas Gkolfakis, Saurabh Chandan, Alberto Tringali, Monique T Barakat, Cesare Hassan, Alessandro Repici, Antonio Facciorusso

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Article in Digestive diseases and sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Etiological treatment of gallstone acute pancreatitis.World journal of gastrointestinal surgery · 2025
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Daryl RamaiDivision of Gastroenterology and Hepatology, University of Utah Health, Salt Lake City, UT, USA. Daryl.Ramai@hsc.utah.edu.ORCID 0000-0002-2460-7806
Joseph HeatonDepartment of Medicine, Jersey Shore University Medical Center, Neptune City, NJ, USA.
Andrew OfosuDivision of Digestive Diseases, University of Cincinnati, Cincinnati, OH, USA.
Paraskevas GkolfakisDepartment of Gastroenterology, Hepatopancreatology, and Digestive Oncology, CUB Erasme Hospital, Université Libre de Bruxelles (ULB), Brussels, Belgium.
Saurabh ChandanDivision of Gastroenterology & Hepatology, CHI Health Creighton University Medical Center, Omaha, NE, USA.
Alberto TringaliEndoscopy Unit, Conegliano Hospital Italy, Conegliano, Italy.
Monique T BarakatDivision of Gastroenterology, Stanford University, Stanford, CA, USA.
Cesare HassanEndoscopic Unit, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Milan, Italy.
Alessandro RepiciEndoscopic Unit, Department of Gastroenterology, IRCCS Humanitas Research Hospital, Milan, Italy.
Antonio FacciorussoSection of Gastroenterology, Department of Medical Sciences, University of Foggia, 71122, Foggia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsPancreaticobiliary diseases are common in the elderly. To this end, frailty represents a state of vulnerability that should be considered when assessing the risks and benefits of therapeutic endoscopic procedures. We aim to determine the rate of readmissions and clinical outcomes using the validated Hospital Frailty Risk Score in patients undergoing endoscopic retrograde cholangiopancreatography (ERCP).

methodsUsing the National Readmissions Database, we identified patients with an admission diagnosis of cholangitis with obstructive stone from 2016 to 2019. Patients were determined to be of low frailty risk with a score of < 5, while patients of medium to high frailty risk had a score of > 5.

resultsDuring the study period, 5751 patients were identified with acute cholangitis with obstructing stone. Mean age of index admissions was 69.4 years and 51.8% were female. From the total cohort, 5119 (89.2%) patients underwent therapeutic ERCP, 38.0% (n = 1947) of whom were regarded as frail (risk score > 5). Following ERCP, frail patients had a less but statistically insignificant readmission rate compared to non-frail patients (2.76% vs 4.05%, p = 0.450). However, compared to non-frail patients, frail patients experienced higher post-ERCP complications (6.20% vs 14.63%, p < 0.001). Frail patients were more likely to have longer lengths of stay, higher hospital cost, and mortality risk.

conclusionERCP is not a risk factor for readmission among frail patients. However, frail patients are at higher risk for procedure-related complications, healthcare utilization, and mortality.

Indexed as

CholangitisCholelithiasisFrailtyAgedCholangiopancreatography, Endoscopic RetrogradeFemaleHumansMaleRetrospective StudiesRisk FactorsAcute cholangitisEndoscopyERCPFrailtyHealthcare utilizationReadmission

Identifiers

PMID37368202

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.