Evidence map›Paper›PMID 37368076›Full record

ArticleAMB Express2023

Plasma activated Ezhangfeng Cuji as innovative antifungal agent and its inactivation mechanism.

Lin Lin, Yue Zhuo, Qiran Dong, Chunjun Yang, Cheng Cheng, Taofeng Liu

Abstract read
In one paragraph

Article in AMB Express, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Cold atmospheric plasma therapy for Malassezia folliculitis: Laboratory investigations and a randomized clinical trial.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2024
    Trial
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lin LinThe Postgraduate School of Anhui, University of Chinese Medicine, Hefei, 230012, People's Republic of China.
Yue ZhuoDepartment of Dermatology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, People's Republic of China.
Qiran DongDepartment of Dermatology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, People's Republic of China.
Chunjun YangDepartment of Dermatology, The Second Affiliated Hospital, Anhui Medical University, Hefei, 230601, People's Republic of China.
Cheng ChengInstitute of Plasma Physics, Chinese Academy of Sciences, Hefei, 230031, People's Republic of China.ORCID http://orcid.org/0000-0002-5007-4695
Taofeng LiuDepartment of Dermatology, The First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, 230012, People's Republic of China. azyltf@163.com.ORCID http://orcid.org/0000-0001-9621-7885

Funding

Natural Science Foundation of Anhui Province 1908085MA29the Clinical Medicine Discipline Construction Project of Anhui Medical University in 2021 2021lcxk028the National Natural Science Foundation of China 51777206the National Natural Science Foundation of China U20A20372the University Synergy Innovation Program of Anhui Province GXXT-2020-064
6 · The paper itself

Abstract

Candida albicans is a highly drug-resistant fungus for which new treatments are urgently needed due to the lack of clinically effective options. In this study, we evaluated the antifungal activity and mechanism of plasma-activated Ezhangfeng Cuji (PAEC) against Candida albicans and compared it with physiological saline (PS), plasma-activated physiological saline (PAPS) and Ezhangfeng Cuji (EC). After dielectric barrier discharge (DBD) plasma treatment with EC for 20 min followed by a 10 min immersion of Candida albicans, the fungus was reduced by approximately 3 orders of magnitude. High performance liquid chromatography (HPLC) results showed an increase of 41.18% and 129.88% in the concentration of oxymatrine and rhein, respectively, after plasma-treated EC. The concentrations of reactive species (RS), such as H

Indexed as

Candida albicansFungal structureIn vitro antifungal effectPlasma activated Ezhangfeng CujiVirulence factor

Identifiers

PMID37368076
PMCPMC10299983

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.