Evidence map›Paper›PMID 37368046›Full record

ReviewFunctional & integrative genomics2023

Flavonoids: a review on biosynthesis and transportation mechanism in plants.

Muhammad Aamir Manzoor, Irfan Ali Sabir, Iftikhar Hussain Shah, Muhammad Waheed Riaz, Shamsur Rehman, Cheng Song, Gouhui Li, M Sanaullah Malik, Ghulam Abbas Ashraf, Muhammad Sajjad Haider and 2 more

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Functional & integrative genomics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Comparative transcriptomics of anthocyanin accumulation in the pericarp of pigmented purple corn.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026
    Article
  7. Article
  8. Article
  9. Review
  10. Transcriptomic Insights into Anthocyanin Biosynthesis inInternational journal of molecular sciences · 2025
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Genome-Wide Identification ofInternational journal of molecular sciences · 2024
    Article
  17. Broccoli (Frontiers in pharmacology · 2024
    Article
  18. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Muhammad Aamir Manzoor *School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Irfan Ali Sabir *School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Iftikhar Hussain ShahSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Muhammad Waheed RiazZhejiang Provincial Key Laboratory of Resources Protection and Innovation of Traditional Chinese Medicine, Zhejiang A&F University, Hangzhou, China.
Shamsur RehmanKey Laboratory of Forest Genetics and Biotechnology, College of Biology and the Environment, Nanjing Forestry University, Ministry of Education, Nanjing, China.
Cheng SongAnhui Engineering Research Center for Eco-Agriculture of Traditional Chinese Medicine, College of Biological and Pharmaceutical Engineering, West Anhui University, Luan, 237012, China.
Gouhui LiAnhui Engineering Research Center for Eco-Agriculture of Traditional Chinese Medicine, College of Biological and Pharmaceutical Engineering, West Anhui University, Luan, 237012, China.
M Sanaullah MalikSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China.
Ghulam Abbas AshrafKey Laboratory of Integrated Regulation and Resources Development On Shallow Lake of Ministry of Education, College of Environment, Hohai University, Nanjing, 210098, People's Republic of China.
Muhammad Sajjad HaiderDepartment of Forestry, College of Agriculture, University of Sargodha, Sargodha, 40100, Pakistan.
Yunpeng CaoCAS Key Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Chinese Academy of Sciences, Wuhan, 430074, China. xfcypeng@126.com.
Muhammad AbdullahSchool of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China. abdullahpadana@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, significant progress has been made in understanding the biosynthetic pathway and regulation of flavonoids through forward genetic approaches. However, there remains a notable gap in knowledge regarding the functional characterization and underlying processes of the transport framework responsible for flavonoid transport. This aspect requires further investigation and clarification to achieve a comprehensive understanding. Presently, there are a total of four proposed transport models associated with flavonoids, namely glutathione S-transferase (GST), multidrug and toxic compound extrusion (MATE), multidrug resistance-associated protein (MRPs), and bilitranslocase-homolog (BTL). Extensive research has been conducted on the proteins and genes related to these transport models. However, despite these efforts, numerous challenges still exist, leaving much to be explored in the future. Gaining a deeper understanding of the mechanisms underlying these transport models holds immense potential for various fields such as metabolic engineering, biotechnological approaches, plant protection, and human health. Therefore, this review aims to provide a comprehensive overview of recent advancements in the understanding of flavonoid transport mechanisms. By doing so, we aim to paint a clear and coherent picture of the dynamic trafficking of flavonoids.

Indexed as

FlavonoidsPlantsBiological TransportGene Expression Regulation, PlantGlutathione TransferaseHumansPlant ProteinsFlavonoidsGlutathione TransferasePlant ProteinsAnthocyanin transportationBTLGSTMATEMRPs

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.