Evidence map›Paper›PMID 37367873›Full record

ReviewMetabolites2023

Plant Secondary Metabolites: The Weapons for Biotic Stress Management.

Jameel M Al-Khayri, Ramakrishnan Rashmi, Varsha Toppo, Pranjali Bajrang Chole, Akshatha Banadka, Wudali Narasimha Sudheer, Praveen Nagella, Wael Fathi Shehata, Muneera Qassim Al-Mssallem, Fatima Mohammed Alessa and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 135 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
135citing papers in PubMed, 2 pooled it
148.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

135 citing papers in PubMed, 2 syntheses or guidelines pooled it, 373 citations in OpenAlex.

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  20. Enrichment of Alkaloids fromFoods (Basel, Switzerland) · 2026
    Article

75 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Jameel M Al-KhayriDepartment of Agricultural Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0001-9507-0201
Ramakrishnan RashmiDepartment of Life Sciences, CHRIST (Deemed to be University), Bangalore 560 029, Karnataka, India.
Varsha ToppoDepartment of Life Sciences, CHRIST (Deemed to be University), Bangalore 560 029, Karnataka, India.
Pranjali Bajrang CholeDepartment of Life Sciences, CHRIST (Deemed to be University), Bangalore 560 029, Karnataka, India.
Akshatha BanadkaDepartment of Life Sciences, CHRIST (Deemed to be University), Bangalore 560 029, Karnataka, India.ORCID 0000-0003-4269-9617
Wudali Narasimha SudheerDepartment of Life Sciences, CHRIST (Deemed to be University), Bangalore 560 029, Karnataka, India.ORCID 0000-0003-4238-3639
Praveen NagellaDepartment of Life Sciences, CHRIST (Deemed to be University), Bangalore 560 029, Karnataka, India.
Wael Fathi ShehataDepartment of Agricultural Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Muneera Qassim Al-MssallemDepartment of Food Science and Nutrition, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.
Fatima Mohammed AlessaDepartment of Food Science and Nutrition, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0001-5593-4589
Mustafa Ibrahim AlmaghaslaDepartment of Arid Land Agriculture, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0002-2834-3318
Adel Abdel-Sabour RezkDepartment of Agricultural Biotechnology, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi Arabia.ORCID 0000-0003-0259-8387
Christ University · INKing Faisal University · SAAgricultural Research Center · EG

Funding

Deanship of Scientific Research, Vice Presidency for Graduate Studies and Scientific Research, King Faisal University, Saudi Arabia Project No. GRANT0000
6 · The paper itself

Abstract

The rise in global temperature also favors the multiplication of pests and pathogens, which calls into question global food security. Plants have developed special coping mechanisms since they are sessile and lack an immune system. These mechanisms use a variety of secondary metabolites as weapons to avoid obstacles, adapt to their changing environment, and survive in less-than-ideal circumstances. Plant secondary metabolites include phenolic compounds, alkaloids, glycosides, and terpenoids, which are stored in specialized structures such as latex, trichomes, resin ducts, etc. Secondary metabolites help the plants to be safe from biotic stressors, either by repelling them or attracting their enemies, or exerting toxic effects on them. Modern omics technologies enable the elucidation of the structural and functional properties of these metabolites along with their biosynthesis. A better understanding of the enzymatic regulations and molecular mechanisms aids in the exploitation of secondary metabolites in modern pest management approaches such as biopesticides and integrated pest management. The current review provides an overview of the major plant secondary metabolites that play significant roles in enhancing biotic stress tolerance. It examines their involvement in both indirect and direct defense mechanisms, as well as their storage within plant tissues. Additionally, this review explores the importance of metabolomics approaches in elucidating the significance of secondary metabolites in biotic stress tolerance. The application of metabolic engineering in breeding for biotic stress resistance is discussed, along with the exploitation of secondary metabolites for sustainable pest management.

Indexed as

aposematic signalsbiopesticidesbiotic stresscompanion farmingfeeding deterrentsmetabolomics engineeringplant secondary metabolites

Identifiers

PMID37367873
PMCPMC10302943
OpenAlexW4379052550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.