Evidence map›Paper›PMID 37367841›Full record

ArticleMetabolites2023

Untargeted Metabolomic Analysis of Sjögren-Larsson Syndrome Reveals a Distinctive Pattern of Multiple Disrupted Biochemical Pathways.

Hongying Daisy Dai, Fang Qiu, Kimberly Jackson, Marcus Fruttiger, William B Rizzo

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Central Precocious Puberty and Sjogren-Larsson Syndrome in a Child: A Rare Case Report.Clinical, cosmetic and investigational dermatology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Hongying Daisy DaiDepartment of Biostatistics, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Fang QiuDepartment of Biostatistics, University of Nebraska Medical Center, Omaha, NE 68198, USA.
Kimberly JacksonMetabolon Inc., Morrisville, NC 27560, USA.
Marcus FruttigerUCL Institute of Ophthalmology, University College London, London EC1V 9EL, UK.ORCID 0000-0002-6962-5485
William B RizzoDepartment of Pediatrics and Child Health Research Center, University of Nebraska Medical Center, Omaha, NE 68198, USA.ORCID 0000-0002-3686-0518
University of Nebraska Medical Center · USChildren's Hospital & Medical Center · USMetabolon (United States) · USUniversity College London · GB

Funding

Sterol and Isoprenoid Diseases Consortium Supplement 2018U54HD061939 · NICHD · UNIVERSITY OF NEBRASKA MEDICAL CENTER · PI RIZZO, WILLIAM B. · 2009 to 2018
$6.6M
NICHD NIH HHS U54 HD061939
6 · The paper itself

Abstract

Sjögren-Larsson syndrome (SLS) is a rare inherited neurocutaneous disease characterized by ichthyosis, spastic diplegia or tetraplegia, intellectual disability and a distinctive retinopathy. SLS is caused by bi-allelic mutations in

Indexed as

fatty alcoholfatty aldehydeichthyosisintellectual disabilitylipid metabolismpathogenesisspasticity

Identifiers

PMID37367841
PMCPMC10301067
OpenAlexW4378083497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.