Evidence map›Paper›PMID 37367742›Full record

ArticleMedical sciences (Basel, Switzerland)2023

Safety and Efficacy of Corneal Cross-Linking in Patients Affected by Keratoconus: Long-Term Results.

Karl Anders Knutsson, Paola Noemi Genovese, Giorgio Paganoni, Oriella Ambrosio, Giulio Ferrari, Arianna Zennato, Michela Caccia, Madeleine Cataldo, Paolo Rama

Open access · goldAbstract read
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Trends in the Management of Keratoconus in Australia.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Karl Anders KnutssonCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.ORCID 0000-0002-9615-2839
Paola Noemi GenoveseCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.
Giorgio PaganoniCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.
Oriella AmbrosioCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.
Giulio FerrariCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.ORCID 0000-0001-6474-9908
Arianna ZennatoCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.
Michela CacciaCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.
Madeleine CataldoCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.
Paolo RamaCornea and Ocular Surface Unit, San Raffaele Scientific Institute, Via Olgettina 60, 20132 Milan, Italy.
San Raffaele University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study evaluated the effectiveness and safety of corneal collagen cross-linking (CXL). A total of 886 eyes with progressive keratoconus were enrolled in a retrospective cohort study in a tertiary care university hospital. CXL was performed using a standard epithelium-off Dresden protocol. Visual outcomes, maximum keratometry (Kmax), demarcation line measurements, and complications were recorded. Visual outcomes and keratometric data were analyzed in a subgroup comprising 610 eyes. Uncorrected distance visual acuity (UDVA) improved from 0.49 ± 0.38 LogMAR to 0.47 ± 0.39 LogMAR (

Indexed as

KeratoconusPhotochemotherapyCollagenCorneal Cross-LinkingCorneal TopographyCross-Linking ReagentsFollow-Up StudiesHumansPhotosensitizing AgentsRetrospective StudiesRiboflavinUltraviolet RaysCollagenCross-Linking ReagentsPhotosensitizing AgentsRiboflavincorneal collagen cross-linkingcorneal ectasiakeratoconus

Identifiers

PMID37367742
PMCPMC10302271
OpenAlexW4381252070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.