Evidence map›Paper›PMID 37367725›Full record

ArticleBrain and behavior2023

Development and clinical feasibility study of a brief version of an addiction-focused phenotyping battery in females receiving buprenorphine for opioid use disorder.

Anna Beth Parlier-Ahmad, Michelle Eglovitch, Catherine Legge, Lori A Keyser-Marcus, James M Bjork, Amanda Adams, Tanya Ramey, Frederick Gerard Moeller, Caitlin E Martin

Abstract read
In one paragraph

Article in Brain and behavior, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna Beth Parlier-AhmadDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0002-6862-9548
Michelle EglovitchDepartment of Psychology, Virginia Commonwealth University, Richmond, Virginia, USA.
Catherine LeggeSchool of Medicine, Virginia Commonwealth University, Richmond, Virginia, USA.
Lori A Keyser-MarcusInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia, USA.
James M BjorkInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia, USA.
Amanda AdamsInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia, USA.
Tanya RameyNational Institute of Drug Abuse, Bethesda, Maryland, USA.
Frederick Gerard MoellerInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia, USA.
Caitlin E MartinInstitute for Drug and Alcohol Studies, Virginia Commonwealth University, Richmond, Virginia, USA.ORCID 0000-0001-5560-458X

Funding

Research Supplement to Promote Diversity in Health Related ResearchUL1TR002649 · NCATS · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2018 to 2022
$19.1M
TRAINING IN THE PHARMACOLOGY OF ABUSED DRUGST32DA007027 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI William L. Dewey · 1985 to 2026
$14.7M
Preclinical Assessment of Compounds for Cocaine Use Disorder (CocUD)U54DA038999 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MOELLER, FREDERICK GERARD · 2014 to 2018
$6.8M
Olanzapine Augmentation in OUD Patients on Buprenorphine-Naloxone with Comorbid Symptoms of Serious Mental Illness (SMI): A Prospective Observational 8-week Pilot StudyUG1DA050207 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI ARIAS, ALBERT JOSEPH, MOELLER, FREDERICK GERARD · 2020 to 2024
$3.1M
Adaptation and Refinement of a Clinically Applicable Phenotypic Battery to Individualize Opioid Use Disorder Treatment for Women Through the Postpartum PeriodK23DA053507 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI MARTIN, CAITLIN EILEEN · 2021 to 2025
$1.0M
NCATS NIH HHS UL1 TR002649NIDA NIH HHS K23 DA053507NIDA NIH HHS T32 DA007027NIDA NIH HHS U54 DA038999NIDA NIH HHS UG1 DA050207
6 · The paper itself

Abstract

introductionWe aimed to streamline the NIDA Phenotyping Assessment Battery (PhAB), a package of self-report scales and neurobehavioral tasks used in substance use disorder (SUD) clinical trials, for clinical administration ease. Tailoring the PhAB to shorten administration time for a treatment setting is critical to expanding its acceptability in SUD clinical trials. This study's primary objectives were to develop a brief version of PhAB (PhAB-B) and assess its operational feasibility and acceptability in a female clinical treatment sample.

methodsAssessments of the original PhAB were evaluated along several criteria to identify a subset for the PhAB-B. Non-pregnant females (N=55) between ages 18-65, stabilized on buprenorphine for opioid use disorder (OUD) at an outpatient addiction clinic, completed this abbreviated battery remotely or after a provider visit in clinic. Participant satisfaction questions were administered. REDCap recorded the time to complete PhAB-B measures.

resultsThe PhAB-B included 11 measures that probed reward, cognition, negative emotionality, interoception, metacognition, and sleep. Participants who completed the PhAB-B (N =55) were 36.1 ± 8.9 years of age, White (54.5%), Black (34.5%), and non-Latinx (96.0%). Most participants completed the PhAB-B remotely (n = 42, 76.4%). Some participants completed it in-person (n = 13, 23.6%). PhAB-B mean completion time was 23.0 ± 12.0 min. Participant experiences were positive, and 96% of whom reported that they would participate in the study again.

conclusionOur findings support the clinical feasibility and acceptability of the PhAB-B among a female opioid use disorder outpatient addiction treatment sample. Future studies should assess the PhAB-B psychometric properties among broader treatment samples.

Indexed as

Behavior, AddictiveBuprenorphineOpioid-Related DisordersFeasibility StudiesFemaleHumansOpiate Substitution TreatmentBuprenorphinebuprenorphineneurofunctionopioid use disorderPhenotyping Assessment Battery (PhAB)

Identifiers

PMID37367725
PMCPMC10454248

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.