Evidence map›Paper›PMID 37367708›Full record

ArticleThe Journal of allergy and clinical immunology2023

Emapalumab as bridge to hematopoietic cell transplant for STAT1 gain-of-function mutations.

Binni Kunvarjee, Alan Bidgoli, Rebecca Pellett Madan, Esther Vidal, Devin McAvoy, Kinga K Hosszu, Andromachi Scaradavou, Barbara G Spitzer, Kevin J Curran, Maria Cancio and 6 more

Open access · bronzeAbstract readLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Infections in Inborn Errors of STATs.Pathogens (Basel, Switzerland) · 2024
    Review
  8. Article
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Binni KunvarjeeDepartment of Pharmacy, Memorial Sloan Kettering Cancer Center, New York, NY.
Alan BidgoliPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Rebecca Pellett MadanDepartment of Pediatrics, NYU Grossman School of Medicine and Hassenfeld Children's Hospital at NYU Langone, New York, NY.
Esther VidalImmune Discovery and Modeling Service, Sloan Kettering Institute, New York, NY.
Devin McAvoyImmune Discovery and Modeling Service, Sloan Kettering Institute, New York, NY.
Kinga K HosszuImmune Discovery and Modeling Service, Sloan Kettering Institute, New York, NY.
Andromachi ScaradavouPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Barbara G SpitzerPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Kevin J CurranPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Maria CancioPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Andrew C HarrisPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Richard J O'ReillyPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Andrew L KungPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Susan ProckopHematopoietic Stem Cell Transplant Program, Dana-Farber/Boston Children's Cancer and Blood Disorders Center, Boston, Mass.
Jaap Jan BoelensPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY.
Joseph H OvedPediatric Bone Marrow Transplant and Cellular Therapy Program, MSK Kids, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address: ovedj@mskcc.org.
Memorial Sloan Kettering Cancer Center · USKettering University · USDana-Farber/Boston Children's Cancer and Blood Disorders Center · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
FDA HHS R01 FD007829FDA HHS R01 FD008175NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Candidiasis, Chronic MucocutaneousHematopoietic Stem Cell TransplantationAntibodies, MonoclonalAntibodies, NeutralizingGain of Function MutationHumansSTAT1 Transcription FactorAntibodies, MonoclonalAntibodies, NeutralizingEmapalumabSTAT1 protein, humanSTAT1 Transcription Factor

Identifiers

PMID37367708
PMCPMC11066755
OpenAlexW4382051749

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.