Evidence map›Paper›PMID 37367693›Full record

ArticleMarine drugs2023

Analogs of 6-Bromohypaphorine with Increased Agonist Potency for α7 Nicotinic Receptor as Anti-Inflammatory Analgesic Agents.

Igor A Ivanov, Andrei E Siniavin, Victor A Palikov, Dmitry A Senko, Irina V Shelukhina, Lyubov A Epifanova, Lucy O Ojomoko, Svetlana Y Belukhina, Nikita A Prokopev, Mariia A Landau and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 4 institutions in 1 country.

Igor A IvanovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Andrei E SiniavinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0001-7576-2059
Victor A PalikovThe Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
Dmitry A SenkoCenter Neurobiology and Brain Restoration, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.
Irina V ShelukhinaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Lyubov A EpifanovaShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Lucy O OjomokoShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Svetlana Y BelukhinaCenter of Life Sciences, Skolkovo Institute of Science and Technology, 121205 Moscow, Russia.
Nikita A ProkopevDepartment of Biology, M.V. Lomonosov Moscow State University, 119991 Moscow, Russia.
Mariia A LandauMoscow Institute of Physics and Technology, 141701 Dolgoprudny, Russia.
Yulia A PalikovaThe Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0001-9547-0686
Vitaly A KazakovThe Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
Natalia A BorozdinaThe Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-2320-655X
Arina V BervinovaThe Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.
Igor A DyachenkoThe Branch of the Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 142290 Pushchino, Russia.ORCID 0000-0002-3053-2804
Igor E KasheverovShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.
Victor I TsetlinShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-7980-6191
Denis S KudryavtsevShemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 117997 Moscow, Russia.ORCID 0000-0002-0313-9193
Institute of Bioorganic Chemistry · RUSkolkovo Institute of Science and Technology · RULomonosov Moscow State University · RUMoscow Institute of Physics and Technology · RU

Funding

Russian Science Foundation 21-74-10092
6 · The paper itself

Abstract

Hypaphorines, tryptophan derivatives, have anti-inflammatory activity, but their mechanism of action was largely unknown. Marine alkaloid L-6-bromohypaphorine with EC

Indexed as

alpha7 Nicotinic Acetylcholine ReceptorReceptors, NicotinicAnalgesicsAnimalsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalHyperalgesiaRatsTryptophanalpha7 Nicotinic Acetylcholine ReceptorAnalgesicsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalL-6-bromohypaporphineReceptors, NicotinicTryptophanagonisthypaphorinesinflammationligandnAChRpotencyα7 nicotinic acetylcholine receptor

Identifiers

PMID37367693
PMCPMC10305119
OpenAlexW4381663098

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.