Evidence map›Paper›PMID 37367683›Full record

ArticleMarine drugs2023

High Solubility and Bioavailability of Lobster Shell-Derived Calcium for Significantly Proliferating Bone and Skin Cells In Vitro.

Trung T Nguyen, Thanh Hoang, Tuyet Pham, Vi Khanh Truong, Xuan Luo, Jian Qin, Wei Zhang

Open access · goldAbstract read
In one paragraph

Article in Marine drugs, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Trung T NguyenCollege of Science and Engineering, Flinders University, Adelaide, SA 5042, Australia.
Thanh HoangCollege of Science and Engineering, Flinders University, Adelaide, SA 5042, Australia.
Tuyet PhamBiomedical Nanoengineering Laboratory, College of Medicine and Public Health, Flinders University, Adelaide, SA 5042, Australia.
Vi Khanh TruongBiomedical Nanoengineering Laboratory, College of Medicine and Public Health, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0002-6016-6438
Xuan LuoFlinders Institute for Nanoscale Science and Technology, College of Science and Engineering, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0002-8811-3143
Jian QinCollege of Science and Engineering, Flinders University, Adelaide, SA 5042, Australia.ORCID 0000-0003-2448-8058
Wei ZhangAdvanced Marine Biomanufacturing Laboratory, Centre for Marine Bioproduct Development, College of Medicine and Public Health, Flinders University, Adelaide, SA 5042, Australia.
Flinders University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Shell wastes pose environmental and financial burdens to the shellfish industry. Utilizing these undervalued shells for commercial chitin production could minimize their adverse impacts while maximizing economic value. Shell chitin conventionally produced through harsh chemical processes is environmentally unfriendly and infeasible for recovering compatible proteins and minerals for value-added products. However, we recently developed a microwave-intensified biorefinery that efficiently produced chitin, proteins/peptides, and minerals from lobster shells. Lobster minerals have a calcium-rich composition and biologically originated calcium is more biofunctional for use as a functional, dietary, or nutraceutical ingredient in many commercial products. This has suggested a further investigation of lobster minerals for commercial applications. In this study, the nutritional attributes, functional properties, nutraceutical effects, and cytotoxicity of lobster minerals were analyzed using in vitro simulated gastrointestinal digestion combined with growing bone (MG-63), skin (HaCaT), and macrophage (THP-1) cells. The calcium from the lobster minerals was found to be comparable to that of a commercial calcium supplement (CCS, 139 vs. 148 mg/g). In addition, beef incorporated with lobster minerals (2%,

Indexed as

CalciumNephropidaeAnimalsBiological AvailabilityCaseinsCattleChitinMineralsSolubilityCalciumCaseinsChitinMineralsbone healthlobster minerallobster shellsmicrowave-intensified extractionmulti-product biorefinerynutraceutical calciumvalue-added productswound healing

Identifiers

PMID37367683
PMCPMC10305498
OpenAlexW4380373963

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.