Evidence map›Paper›PMID 37367595›Full record

ReviewJournal of fungi (Basel, Switzerland)2023

Epidemiology, Modern Diagnostics, and the Management of Mucorales Infections.

David Pham, Annaleise R Howard-Jones, Rebecca Sparks, Maurizio Stefani, Varsha Sivalingam, Catriona L Halliday, Justin Beardsley, Sharon C-A Chen

Open access · goldAbstract readReview
In one paragraph

Review in Journal of fungi (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
5.1field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. IntracranialJournal of child neurology · 2025
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Cutaneous mucormycosis confirmed using aFrontiers in medicine · 2026
    Article
  7. Article
  8. Fatal Pharyngeal Cellulitis Caused byInfection and drug resistance · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Case reports in pathology · 2025
    Article
  16. Article
  17. Molecular mechanisms that govern infection and antifungal resistance in Mucorales.Microbiology and molecular biology reviews : MMBR · 2024
    Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

David PhamCentre for Infectious Diseases & Microbiology, Westmead Hospital, Westmead, NSW 2170, Australia.ORCID 0000-0002-0953-4063
Annaleise R Howard-JonesCentre for Infectious Diseases & Microbiology Laboratory Services, NSW Health Pathology-Institute of Clinical Pathology & Medical Research, Westmead Hospital, Westmead, NSW 2170, Australia.ORCID 0000-0002-9756-2813
Rebecca SparksDouglass Hanly Moir Pathology, Sydney, NSW 2113, Australia.
Maurizio StefaniCentre for Infectious Diseases & Microbiology Laboratory Services, NSW Health Pathology-Institute of Clinical Pathology & Medical Research, Westmead Hospital, Westmead, NSW 2170, Australia.
Varsha SivalingamCentre for Infectious Diseases & Microbiology Laboratory Services, NSW Health Pathology-Institute of Clinical Pathology & Medical Research, Westmead Hospital, Westmead, NSW 2170, Australia.ORCID 0000-0002-8834-892X
Catriona L HallidayCentre for Infectious Diseases & Microbiology Laboratory Services, NSW Health Pathology-Institute of Clinical Pathology & Medical Research, Westmead Hospital, Westmead, NSW 2170, Australia.ORCID 0000-0002-0301-7110
Justin BeardsleyCentre for Infectious Diseases & Microbiology, Westmead Hospital, Westmead, NSW 2170, Australia.ORCID 0000-0003-1978-1559
Sharon C-A ChenCentre for Infectious Diseases & Microbiology Laboratory Services, NSW Health Pathology-Institute of Clinical Pathology & Medical Research, Westmead Hospital, Westmead, NSW 2170, Australia.
Westmead Hospital · AUThe University of Sydney · AUDouglass Hanly Moir Pathology · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucormycosis is an uncommon, yet deadly invasive fungal infection caused by the Mucorales moulds. These pathogens are a WHO-assigned high-priority pathogen group, as mucormycosis incidence is increasing, and there is unacceptably high mortality with current antifungal therapies. Current diagnostic methods have inadequate sensitivity and specificity and may have issues with accessibility or turnaround time. Patients with diabetes mellitus and immune compromise are predisposed to infection with these environmental fungi, but COVID-19 has established itself as a new risk factor. Mucorales also cause healthcare-associated outbreaks, and clusters associated with natural disasters have also been identified. Robust epidemiological surveillance into burden of disease, at-risk populations, and emerging pathogens is required. Emerging serological and molecular techniques may offer a faster route to diagnosis, while newly developed antifungal agents show promise in preliminary studies. Equitable access to these emerging diagnostic techniques and antifungal therapies will be key in identifying and treating mucormycosis, as delayed initiation of therapy is associated with higher mortality.

Indexed as

antifungal agentsdiagnosticsDNA sequencingepidemiologyMucoralesmucormycosis

Identifiers

PMID37367595
PMCPMC10304757
OpenAlexW4380629452

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.