Evidence map›Paper›PMID 37367399›Full record

ArticleJournal of cardiovascular development and disease2023

Morbidity and Mortality of Heterotopic Partial Heart Transplantation in Rodent Models.

Savannah Skidmore, Morgan A Hill, Katherine Bishara, Haley Konsek, Jennie H Kwon, Kelvin G M Brockbank, Taufiek Konrad Rajab

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Surgical Protocol for Partial Heart Transplantation in Growing Piglets.World journal for pediatric & congenital heart surgery · 2024
    Article
  3. Animal models for partial heart transplantation.Pediatric transplantation · 2024
    Review
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Savannah SkidmoreCollege of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Morgan A HillCollege of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.
Katherine BisharaCollege of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0002-9785-9836
Haley KonsekCollege of Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.ORCID 0000-0003-0202-0374
Jennie H KwonDepartment of Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Kelvin G M BrockbankTissue Testing Technologies LLC, North Charleston, SC 29425, USA.ORCID 0000-0002-2718-3455
Taufiek Konrad RajabDepartment of Pediatric Cardiothoracic Surgery, Medical University of South Carolina, Charleston, SC 29425, USA.
Medical University of South Carolina · USClemson University · US

Funding

Evaluation of growth potential of ice-free vitrified heart valves in a pediatric porcine model.R41HL169059 · NHLBI · TISSUE TESTING TECHNOLOGIES, LLC · PI RAJAB, TAUFIEK KONRAD · 2023 to 2023
$611k
NHLBI NIH HHS R41 HL169059
6 · The paper itself

Abstract

Unrepairable congenital heart valve disease is an unsolved problem in pediatric cardiac surgery because there are no growing heart valve implants. Partial heart transplantation is a new type of transplant that aims to solve this problem. In order to study the unique transplant biology of partial heart transplantation, animal models are necessary. This study aimed to assess the morbidity and mortality of heterotopic partial heart transplantation in rodent models. This study assessed two models. The first model involved transplanting heart valves from donor animals into the abdominal aortic position in the recipient animals. The second model involved transplanting heart valve leaflets into the renal subcapsular position of the recipient animals. A total of 33 animals underwent heterotopic partial heart transplantation in the abdominal aortic position. The results of this model found a 60.61% (

Indexed as

animal modelcongenital cardiac surgerypartial heart transplantationpediatric cardiac surgeryrodentvalve dysfunction

Identifiers

PMID37367399
PMCPMC10299259
OpenAlexW4378527909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.