Evidence map›Paper›PMID 37367396›Full record

ArticleJournal of cardiovascular development and disease2023

Left Ventricular Ejection Fraction Association with Acute Ischemic Stroke Outcomes in Patients Undergoing Thrombolysis.

Ryan C H Chee, Norman H Lin, Jamie S Y Ho, Aloysius S T Leow, Tony Y W Li, Edward C Y Lee, Mark Y Chan, William K F Kong, Tiong-Cheng Yeo, Ping Chai and 6 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular development and disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Prediction of trends in unfavorable prognosis in patients with acute ischemic stroke according to low left ventricular ejection fraction levels.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2024
    Pooled it
  2. Article
  3. Echocardiographic predictors of futile recanalization in acute ischemic stroke.Revista da Associacao Medica Brasileira (1992) · 2025
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Ryan C H CheeDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Norman H LinDepartment of Cardiology, National University Heart Centre Singapore, Singapore 119074, Singapore.ORCID 0000-0002-6329-4603
Jamie S Y HoDepartment of Cardiology, National University Heart Centre Singapore, Singapore 119074, Singapore.
Aloysius S T LeowDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Tony Y W LiDepartment of Cardiology, National University Heart Centre Singapore, Singapore 119074, Singapore.
Edward C Y LeeDepartment of Cardiology, National University Heart Centre Singapore, Singapore 119074, Singapore.
Mark Y ChanDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.ORCID 0000-0003-0389-7450
William K F KongDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Tiong-Cheng YeoDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Ping ChaiDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
James W L YipDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Kian-Keong PohDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Vijay K SharmaDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Leonard L L YeoDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.
Benjamin Y Q TanDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.ORCID 0000-0003-1824-9077
Ching-Hui SiaDepartment of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore.ORCID 0000-0002-2764-2869
National University of Singapore · SGNational University Heart Centre Singapore · SG

Funding

National University of Singapore, Yong Loo Lin School of Medicine's Junior Academic Fellowship Scheme National University of Singapore, Yong Loo Lin School of Medicine's Junior Academic Fellowship Scheme
6 · The paper itself

Abstract

(1) Background: Little is known about how left ventricular systolic dysfunction (LVSD) affects functional and clinical outcomes in acute ischemic stroke (AIS) patients undergoing thrombolysis; (2) Methods: A retrospective observational study conducted between 2006 and 2018 included 937 consecutive AIS patients undergoing thrombolysis. LVSD was defined as left ventricular ejection fraction (LVEF) < 50%. Univariate and multivariate binary logistic regression analysis was performed for demographic characteristics. Ordinal shift regression was used for functional modified Rankin Scale (mRS) outcome at 3 months. Survival analysis of mortality, heart failure (HF) admission, myocardial infarction (MI) and stroke/transient ischemic attack (TIA) was evaluated with a Cox-proportional hazards model; (3) Results: LVSD patients in comparison with LVEF ≥ 50% patients accounted for 190 and 747 patients, respectively. LVSD patients had more comorbidities including diabetes mellitus (100 (52.6%) vs. 280 (37.5%),

Indexed as

acute ischemic strokefunctional and clinical outcomesIV thrombolysisleft ventricular systolic dysfunction

Identifiers

PMID37367396
PMCPMC10299251
OpenAlexW4378469557

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.