Evidence map›Paper›PMID 37367273›Full record

ArticleJournal of functional biomaterials2023

Analysis of the Effect of Thickness on the Performance of Polymeric Heart Valves.

Jingyuan Zhou, Yijing Li, Tao Li, Xiaobao Tian, Yan Xiong, Yu Chen

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. [Numerical simulation study on the influence of free edge configuration on the performance of polymeric heart valves].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingyuan ZhouDepartment of Applied Mechanics, Sichuan University, Chengdu 610065, China.
Yijing LiCollege of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Tao LiCollege of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Xiaobao TianDepartment of Applied Mechanics, Sichuan University, Chengdu 610065, China.
Yan XiongCollege of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Yu ChenDepartment of Applied Mechanics, Sichuan University, Chengdu 610065, China.ORCID 0000-0002-8931-8079

Funding

the National Key R&D Program of China 12172239
6 · The paper itself

Abstract

Polymeric heart valves (PHVs) are a promising and more affordable alternative to mechanical heart valves (MHVs) and bioprosthetic heart valves (BHVs). Materials with good durability and biocompatibility used for PHVs have always been the research focus in the field of prosthetic heart valves for many years, and leaflet thickness is a major design parameter for PHVs. The study aims to discuss the relationship between material properties and valve thickness, provided that the basic functions of PHVs are qualified. The fluid-structure interaction (FSI) approach was employed to obtain a more reliable solution of the effective orifice area (EOA), regurgitant fraction (RF), and stress and strain distribution of the valves with different thicknesses under three materials: Carbothane PC-3585A, xSIBS and SIBS-CNTs. This study demonstrates that the smaller elastic modulus of Carbothane PC-3585A allowed for a thicker valve (>0.3 mm) to be produced, while for materials with an elastic modulus higher than that of xSIBS (2.8 MPa), a thickness less than 0.2 mm would be a good attempt to meet the RF standard. What is more, when the elastic modulus is higher than 23.9 MPa, the thickness of the PHV is recommended to be 0.l-0.15 mm. Reducing the RF is one of the directions of PHV optimization in the future. Reducing the thickness and improving other design parameters are reliable means to reduce the RF for materials with high and low elastic modulus, respectively.

Indexed as

fluid–structure interaction (FSI)polymeric heart valves (PHVs)strainstressthickness

Identifiers

PMID37367273
PMCPMC10299598

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.