Evidence map›Paper›PMID 37367226›Full record

ArticleJournal of virology2023

Zebrafish MAP2K7 Simultaneously Enhances Host IRF7 Stability and Degrades Spring Viremia of Carp Virus P Protein via Ubiquitination Pathway.

Can Zhang, Long-Feng Lu, Zhuo-Cong Li, Ke-Jia Han, Xue-Li Wang, Dan-Dan Chen, Feng Xiong, Xi-Yin Li, Li Zhou, Feng Ge and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Can ZhangInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Long-Feng LuInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Zhuo-Cong LiInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Ke-Jia HanInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Xue-Li WangInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Dan-Dan ChenInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Feng XiongInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Xi-Yin LiInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Li ZhouInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Feng GeInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.ORCID 0000-0002-1032-280X
Shun LiInstitute of Hydrobiology, Chinese Academy of Sciences, Wuhan, China.
Chinese Academy of Sciences · CNDalian Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

During viral infection, host defensive proteins either enhance the host immune response or antagonize viral components directly. In this study, we report on the following two mechanisms employed by zebrafish mitogen-activated protein kinase kinase 7 (MAP2K7) to protect the host during spring viremia of carp virus (SVCV) infection: stabilization of host IRF7 and degradation of SVCV P protein.

Indexed as

Fish DiseasesInterferon Regulatory FactorsMitogen-Activated Protein KinasesRhabdoviridae InfectionsUbiquitinationViral Structural ProteinsAnimalsProtein StabilityProteolysisRhabdoviridaeUp-RegulationZebrafishZebrafish ProteinsInterferon Regulatory FactorsIRF7 protein, zebrafishMitogen-Activated Protein KinasesViral Structural ProteinsZebrafish ProteinsIFNIRF7MAP2K7SVCVubiquitination

Identifiers

PMID37367226
PMCPMC10373533
OpenAlexW4382182175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.