Evidence map›Paper›PMID 37367134›Full record

ArticleGels (Basel, Switzerland)2023

Drying Process of HPMC-Based Hard Capsules: Visual Experiment and Mathematical Modeling.

Chuqi He, Yucheng Yang, Mi Zhang, Kecheng Zhou, Yayan Huang, Na Zhang, Jing Ye, Moses Arowo, Bingde Zheng, Xueqin Zhang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Gels (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.8field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Chuqi HeDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.
Yucheng YangDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.ORCID 0000-0001-8817-1741
Mi ZhangDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.
Kecheng ZhouDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.
Yayan HuangDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.
Na ZhangDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.
Jing YeDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.
Moses ArowoDepartment of Chemical & Process Engineering, Moi University, Nairobi 3900-30100, Kenya.
Bingde ZhengDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.ORCID 0000-0001-9548-1457
Xueqin ZhangDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.
Honghui XuZhejiang Honghui Capsule Co., Ltd., Shaoxing 312500, China.
Meitian XiaoDepartment of Chemical and Pharmaceutical Engineering, School of Chemical Engineering, Huaqiao University, Xiamen 361021, China.
Huaqiao University · CNMoi University · KEZhejiang Medicine (China) · CN

Funding

Fund Project the Foreign Cooperation Project of Fujian Province 2020I0018, 2021I0016the Fujian Province Marine Economic Development Special FJHJG-L-2022-6the Industry-university-research collaboration project of Xiamen 2022CXY02010the National Nature Science Foundation of China 81703390, 22078120
6 · The paper itself

Abstract

Using plant-based polysaccharide gels to produce hard capsules is a novel application of this technology in the medicinal field, which has garnered significant attention. However, the current manufacturing technology, particularly the drying process, limits its industrialization. The work herein employed an advanced measuring technique and a modified mathematical model to get more insight into the drying process of the capsule. Low field magnetic resonance imaging (LF-MRI) technique is adopted to reveal the distribution of moisture content in the capsule during drying. Furthermore, a modified mathematical model is developed by considering the dynamic variation of the effective moisture diffusivity (

Indexed as

dryingfilmLF-MRImathematical modelingplant-based polysaccharide gels

Identifiers

PMID37367134
PMCPMC10298255
OpenAlexW4379422169

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.