Evidence map›Paper›PMID 37366985›Full record

ReviewBiosensors2023

Molecularly Imprinted Polymer-Based Electrochemical Sensors for the Diagnosis of Infectious Diseases.

Greta Pilvenyte, Vilma Ratautaite, Raimonda Boguzaite, Simonas Ramanavicius, Chien-Fu Chen, Roman Viter, Arunas Ramanavicius

Open access · goldAbstract readReview
In one paragraph

Review in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
6.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 60 citations in OpenAlex.

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  19. Conformable electrochemical devices for closed-loop wound management.Frontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Greta PilvenyteDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology (FTMC), Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-1895-0130
Vilma RatautaiteDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology (FTMC), Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-9931-4397
Raimonda BoguzaiteDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology (FTMC), Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-5178-5907
Simonas RamanaviciusDepartment of Electrochemical Material Science, State Research Institute Center for Physical Sciences and Technology (FTMC), Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.
Chien-Fu ChenInstitute of Applied Mechanics, National Taiwan University, Taipei City 106, Taiwan.
Roman ViterInstitute of Atomic Physics and Spectroscopy, University of Latvia, 19 Raina Blvd., LV-1586 Riga, Latvia.
Arunas RamanaviciusDepartment of Nanotechnology, State Research Institute Center for Physical Sciences and Technology (FTMC), Saulėtekio Av. 3, LT-10257 Vilnius, Lithuania.ORCID 0000-0002-0885-3556
Vilnius University · LTCenter for Physical Sciences and Technology · LTNational Taiwan University · TWSumy State University · UA

Funding

Lietuvos Mokslo Taryba No S-LLT-21-3
6 · The paper itself

Abstract

The appearance of biological molecules, so-called biomarkers in body fluids at abnormal concentrations, is considered a good tool for detecting disease. Biomarkers are usually looked for in the most common body fluids, such as blood, nasopharyngeal fluids, urine, tears, sweat, etc. Even with significant advances in diagnostic technology, many patients with suspected infections receive empiric antimicrobial therapy rather than appropriate treatment, which is driven by rapid identification of the infectious agent, leading to increased antimicrobial resistance. To positively impact healthcare, new tests are needed that are pathogen-specific, easy to use, and produce results quickly. Molecularly imprinted polymer (MIP)-based biosensors can achieve these general goals and have enormous potential for disease detection. This article aimed to overview recent articles dedicated to electrochemical sensors modified with MIP to detect protein-based biomarkers of certain infectious diseases in human beings, particularly the biomarkers of infectious diseases, such as HIV-1, COVID-19, Dengue virus, and others. Some biomarkers, such as C-reactive protein (CRP) found in blood tests, are not specific for a particular disease but are used to identify any inflammation process in the body and are also under consideration in this review. Other biomarkers are specific to a particular disease, e.g., SARS-CoV-2-S spike glycoprotein. This article analyzes the development of electrochemical sensors using molecular imprinting technology and the used materials' influence. The research methods, the application of different electrodes, the influence of the polymers, and the established detection limits are reviewed and compared.

Indexed as

Anti-Infective AgentsCommunicable DiseasesCOVID-19Molecular ImprintingBiomarkersCOVID-19 TestingC-Reactive ProteinElectrochemical TechniquesElectrodesHumansLimit of DetectionMolecularly Imprinted PolymersSARS-CoV-2Anti-Infective AgentsBiomarkersC-Reactive ProteinMolecularly Imprinted Polymerselectrochemical sensorinfectious disease biomarkermolecularly imprinted polymer (MIP)

Identifiers

PMID37366985
PMCPMC10296657
OpenAlexW4379472565

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.