Evidence map›Paper›PMID 37366945›Full record

ArticleBiosensors2023

Modeling of Paper-Based Bi-Material Cantilever Actuator for Microfluidic Biosensors.

Ashutosh Kumar, Hojat Heidari-Bafroui, Nassim Rahmani, Constantine Anagnostopoulos, Mohammad Faghri

Open access · goldAbstract read
In one paragraph

Article in Biosensors, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ashutosh KumarMicrofluidics Laboratory, Department of Mechanical, Industrial and Systems Engineering, University of Rhode Island, 2 East Alumni Avenue, Kingston, RI 02881, USA.ORCID 0000-0002-2563-2130
Hojat Heidari-BafrouiMicrofluidics Laboratory, Department of Mechanical, Industrial and Systems Engineering, University of Rhode Island, 2 East Alumni Avenue, Kingston, RI 02881, USA.ORCID 0000-0002-7236-9558
Nassim RahmaniMicrofluidics Laboratory, Department of Mechanical, Industrial and Systems Engineering, University of Rhode Island, 2 East Alumni Avenue, Kingston, RI 02881, USA.
Constantine AnagnostopoulosMicrofluidics Laboratory, Department of Mechanical, Industrial and Systems Engineering, University of Rhode Island, 2 East Alumni Avenue, Kingston, RI 02881, USA.
Mohammad FaghriMicrofluidics Laboratory, Department of Mechanical, Industrial and Systems Engineering, University of Rhode Island, 2 East Alumni Avenue, Kingston, RI 02881, USA.
University of Rhode Island · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research explores the dynamics of a fluidically loaded Bi-Material cantilever (B-MaC), a critical component of μPADs (microfluidic paper-based analytical devices) used in point-of-care diagnostics. Constructed from Scotch Tape and Whatman Grade 41 filter paper strips, the B-MaC's behavior under fluid imbibition is examined. A capillary fluid flow model is formulated for the B-MaC, adhering to the Lucas-Washburn (LW) equation, and supported by empirical data. This paper further investigates the stress-strain relationship to estimate the modulus of the B-MaC at various saturation levels and to predict the behavior of the fluidically loaded cantilever. The study shows that the Young's modulus of Whatman Grade 41 filter paper drastically decreases to approximately 20 MPa (about 7% of its dry-state value) upon full saturation. This significant decrease in flexural rigidity, in conjunction with the hygroexpansive strain and coefficient of hygroexpansion (empirically deduced to be 0.008), is essential in determining the B-MaC's deflection. The proposed moderate deflection formulation effectively predicts the B-MaC's behavior under fluidic loading, emphasizing the measurement of maximum (tip) deflection using interfacial boundary conditions for the B-MaC's wet and dry regions. This knowledge of tip deflection will prove instrumental in optimizing the design parameters of B-MaCs.

Indexed as

Biosensing TechniquesMicrofluidicsFiltrationLab-On-A-Chip DevicesSoftwareBi-Material cantileverfluid imbibitionhygroexpansion coefficienthygroexpansion strainmodulus of paperpaper-based sensorpaper-based valveWhatman Grade 41 filter paper

Identifiers

PMID37366945
PMCPMC10296547
OpenAlexW4378528186

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.