Evidence map›Paper›PMID 37366878›Full record

ReviewCurrent oncology (Toronto, Ont.)2023

Novel Tools for Diagnosis and Monitoring of AML.

Francesca Guijarro, Marta Garrote, Neus Villamor, Dolors Colomer, Jordi Esteve, Mónica López-Guerra

Open access · goldAbstract readReview
In one paragraph

Review in Current oncology (Toronto, Ont.), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 29 citations in OpenAlex.

  1. Review
  2. Article
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  7. Review
  8. Diagnostic and prognostic relevance ofLeukemia research reports · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Francesca GuijarroHematopathology Section, Pathology Department, Hospital Clinic Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-6376-0929
Marta GarroteHematopathology Section, Pathology Department, Hospital Clinic Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-8571-1466
Neus VillamorHematopathology Section, Pathology Department, Hospital Clinic Barcelona, 08036 Barcelona, Spain.
Dolors ColomerHematopathology Section, Pathology Department, Hospital Clinic Barcelona, 08036 Barcelona, Spain.ORCID 0000-0001-7486-8484
Jordi EsteveInstitut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Mónica López-GuerraHematopathology Section, Pathology Department, Hospital Clinic Barcelona, 08036 Barcelona, Spain.ORCID 0000-0002-5545-0178
Hospital Clínic de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, major advances in the understanding of acute myeloid leukemia (AML) pathogenesis, together with technological progress, have led us into a new era in the diagnosis and follow-up of patients with AML. A combination of immunophenotyping, cytogenetic and molecular studies are required for AML diagnosis, including the use of next-generation sequencing (NGS) gene panels to screen all genetic alterations with diagnostic, prognostic and/or therapeutic value. Regarding AML monitoring, multiparametric flow cytometry and quantitative PCR/RT-PCR are currently the most implemented methodologies for measurable residual disease (MRD) evaluation. Given the limitations of these techniques, there is an urgent need to incorporate new tools for MRD monitoring, such as NGS and digital PCR. This review aims to provide an overview of the different technologies used for AML diagnosis and MRD monitoring and to highlight the limitations and challenges of current versus emerging tools.

Indexed as

Leukemia, Myeloid, AcuteHigh-Throughput Nucleotide SequencingHumansMutationNeoplasm, ResidualPrognosisAMLdiagnosisdigital PCRflow cytometryMRD monitoringNGS

Identifiers

PMID37366878
PMCPMC10297692
OpenAlexW4378087252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.