Evidence map›Paper›PMID 37366539›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2023

Tobacco smoking is associated with combined pulmonary fibrosis and emphysema and worse outcomes in interstitial lung disease.

Dylan Douglas, Layne Keating, Rachel Strykowski, Cathryn T Lee, Nicole Garcia, Kavitha Selvan, Neha Kaushik, Iazsmin Bauer Ventura, Renea Jablonski, Rekha Vij and 4 more

Open access · greenAbstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  3. Review
  4. Article
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  8. Review
  9. The Lung in Rheumatoid Arthritis-Friend or Enemy?International journal of molecular sciences · 2024
    Review
  10. Article
  11. Review
  12. Etiology and Pathogenesis of Rheumatoid Arthritis-Interstitial Lung Disease.International journal of molecular sciences · 2023
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Dylan DouglasSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.ORCID 0000-0001-8321-4327
Layne KeatingSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.
Rachel StrykowskiSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.
Cathryn T LeeSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.ORCID 0000-0002-0963-7505
Nicole GarciaSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.ORCID 0000-0002-1619-3359
Kavitha SelvanSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.
Neha KaushikDivision of Pulmonary and Critical Care, Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States.
Iazsmin Bauer VenturaSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.
Renea JablonskiSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.
Rekha VijSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.
Jonathan H ChungDepartment of Radiology, The University of Chicago, Chicago, Illinois, United States.
Shashi BellamDivision of Pulmonary and Critical Care, Department of Medicine, NorthShore University HealthSystem, Evanston, Illinois, United States.
Mary E StrekSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.
Ayodeji AdegunsoyeSection of Pulmonary and Critical Care, Department of Medicine, The University of Chicago, Chicago, Illinois, United States.ORCID 0000-0002-7015-9610
University of Chicago · USNorthShore University HealthSystem · US

Funding

RESEARCH TRAINING IN RESPIRATORY BIOLOGYT32HL007605 · NHLBI · UNIVERSITY OF CHICAGO · PI Yun Fang, Gokhan M. Mutlu · 1985 to 2026
$18.1M
Pilot Program CoreP30ES027792 · NIEHS · UNIVERSITY OF CHICAGO · PI Gokhan M. Mutlu, Gail S Prins · 2017 to 2026
$13.6M
Improving Pulmonary Fibrosis Classification with Genomics Informed Phenotypic ClustersK23HL146942 · NHLBI · UNIVERSITY OF CHICAGO · PI ADEGUNSOYE, AYODEJI · 2020 to 2024
$810k
NHLBI NIH HHS K23 HL146942NIEHS NIH HHS P30 ES027792
6 · The paper itself

Abstract

Tobacco smoking is an established cause of pulmonary disease whose contribution to interstitial lung disease (ILD) is incompletely characterized. We hypothesized that compared with nonsmokers, subjects who smoked tobacco would differ in their clinical phenotype and have greater mortality. We performed a retrospective cohort study of tobacco smoking in ILD. We evaluated demographic and clinical characteristics, time to clinically meaningful lung function decline (LFD), and mortality in patients stratified by tobacco smoking status (ever vs. never) within a tertiary center ILD registry (2006-2021) and replicated mortality outcomes across four nontertiary medical centers. Data were analyzed by two-sided

Indexed as

EmphysemaIdiopathic Pulmonary FibrosisLung Diseases, InterstitialPulmonary EmphysemaHumansLungMaleRetrospective StudiesTobacco Smokinginterstitial lung diseasemortalitypulmonary fibrosissmokingtobacco

Identifiers

PMID37366539
PMCPMC10396279
OpenAlexW4382181492

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.